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Este documento describe el desarrollo y la funcionalidad de CellMiner, una base de datos relacional y herramienta de consulta para integrar diversos tipos de datos moleculares de las líneas celulares
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How to fill out CellMiner: a relational database and query tool for the NCI-60 cancer cell lines
01
Access the CellMiner website.
02
Create an account or log in if you already have one.
03
Familiarize yourself with the interface, noting the available features.
04
Select the NCI-60 cancer cell lines you are interested in.
05
Use the search and filter options to refine your query criteria.
06
Review the available datasets and choose the relevant data types (e.g., gene expression, drug sensitivity).
07
Utilize the visualization tools to view your results.
08
Download any selected data for further analysis if needed.
Who needs CellMiner: a relational database and query tool for the NCI-60 cancer cell lines?
01
Researchers in cancer biology.
02
Pharmaceutical companies developing cancer therapies.
03
Academics studying cell line characteristics.
04
Clinical researchers looking for drug efficacy data.
05
Data scientists focusing on cancer genomics and bioinformatics.
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People Also Ask about
What is the NCI ADR cell line?
Description: The NCI/ADR-RES cell line is a multidrug-resistant human ovarian cancer cell line derived from the OVCAR-8 parental line.
What is the doubling time of NCI-H460?
NCI-H460 cells are adherent cells growing twice as fast than the A549 cells with a doubling time of 33 hours in RPMI 1640 supplemented with 10% FBS. They can form tumors in both in vitro and in vivo models, including nude mice.
What are NCI 60 cell lines?
The US National Cancer Institute (NCI) 60 human tumour cell line anticancer drug screen (NCI60) was developed in the late 1980s as an in vitro drug-discovery tool intended to supplant the use of transplantable animal tumours in anticancer drug screening.
What type of cell is NCI-H460?
The NCI-H460 cell line was derived by A.F. Gazdar and associates in 1982 from the pleural fluid of a patient with large cell cancer of the lung. modal numbr = 57; range = 53 to 65. This is a hypotriploid human cell line.
What is the difference between NCI-H460 and A549?
Both NCI-H460 and A549 cell lines are derived from lung carcinomas, but NCI-H460 represents large cell carcinoma, while A549 represents adenocarcinoma. This difference in histological subtype influences their characteristics and behavior.
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What is CellMiner: a relational database and query tool for the NCI-60 cancer cell lines?
CellMiner is a web-based relational database that provides a comprehensive resource for exploring the genetic, genomic, and pharmacological data associated with the NCI-60 cancer cell lines, which are a standardized panel of 60 human cancer cell lines used for cancer research.
Who is required to file CellMiner: a relational database and query tool for the NCI-60 cancer cell lines?
Researchers, scientists, and healthcare professionals involved in cancer research and drug discovery are typically the users who would engage with the CellMiner database, although it is accessible to anyone interested in cancer biology.
How to fill out CellMiner: a relational database and query tool for the NCI-60 cancer cell lines?
Users do not 'fill out' CellMiner as it is not a form but rather an interactive tool. Users can search and query the database through its interface to obtain information on specific cell lines, genes, drug responses, and more.
What is the purpose of CellMiner: a relational database and query tool for the NCI-60 cancer cell lines?
The purpose of CellMiner is to integrate and provide access to multidimensional data related to cancer cell lines in order to facilitate research into cancer biology and to assist in the identification of new therapeutic targets and drug candidates.
What information must be reported on CellMiner: a relational database and query tool for the NCI-60 cancer cell lines?
CellMiner reports various types of information including genomic data, gene expression profiles, drug resistance and sensitivity data, and other relevant biological characteristics of the NCI-60 cancer cell lines.
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