Fillable Is a ,-barrel model of the K+ channel energetically feasible - ncbi nlm nih

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Is a ,-barrel model of the K+ channel energetically feasible? Stephen Bogusz and David Busath Section of Physiology, Brown University, Providence, Rhode Island 02912 INTRODUCTION A mutation of Shaker D431 or T449 strongly affects external tetraethylammonium (TEA) binding (1) whereas a mutation of Shaker T441 (2) or NGK2/DRK1 chimera L374 (equivalent to Shaker V443) and chimera V369 (3) affect internal TEA blocking...
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