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Boris preprint first posted online Sep. 27, 2017; DOI: http://dx.doi.org/10.1101/193995. The copyright holder for this preprint (which was not peer reviewed) is the author/funder. It is made available
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To fill out extreme heterogeneity of influenza, follow these points:
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Collect different strains of influenza virus.
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Isolate the viral RNA from each strain.
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Perform genetic sequencing of each strain to determine the nucleotide sequence.
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Analyze the sequences to identify differences and similarities between the strains.
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Use bioinformatics tools to compare the sequences and generate a phylogenetic tree.
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Analyze the phylogenetic tree to understand the evolutionary relationships and divergence of the influenza strains.
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Study the genetic variations in the strains to determine the extent of heterogeneity.
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Document the findings and publish the results for scientific reference.

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