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View Online COMMUNICATION www.rsc.org/chemcomm Chemo Gold-catalyzed cyclo-isomerization of 1,6-diyne-4-en-3-ols to form naphtha ketone derivatives Jiangsu Loan and Raising Liu* Downloaded on 09 February

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How to fill out gold-catalyzed cyclo-isomerization of 16-diyne-4-en-3-ols:

1. Begin by preparing the necessary reagents and equipment for the reaction.
2. Combine the 16-diyne-4-en-3-ols substrate and the gold catalyst in a suitable solvent.
3. Stir the reaction mixture under the appropriate conditions, typically at a specific temperature and for a specific duration.
4. Monitor the progress of the reaction using appropriate analytical techniques, such as TLC or NMR.
5. Once the desired degree of isomerization is achieved, quench the reaction using a suitable quenching agent.
6. Purify the resulting product through techniques such as column chromatography or recrystallization.
7. Analyze the final product to confirm the desired isomerization has occurred.

Who needs gold-catalyzed cyclo-isomerization of 16-diyne-4-en-3-ols:

1. Organic chemists: Organic chemists studying reaction mechanisms, synthetic methodologies, or natural product synthesis may be interested in gold-catalyzed cyclo-isomerization of 16-diyne-4-en-3-ols. This reaction provides a powerful tool for the construction of complex molecular architectures.
2. Medicinal chemists: Medicinal chemists working on the development of new drugs may find gold-catalyzed cyclo-isomerization of 16-diyne-4-en-3-ols useful. This reaction could be employed to introduce structural modifications into drug-like molecules, potentially leading to improved pharmaceutical properties.
3. Material scientists: Material scientists interested in designing and synthesizing novel materials may also be interested in this reaction. The unique reactivity of gold catalysts can enable the formation of complex structures and interfaces, which may have applications in the development of advanced materials with specific properties or functionalities.

Overall, gold-catalyzed cyclo-isomerization of 16-diyne-4-en-3-ols is a versatile and valuable synthetic tool with potential applications in various fields of chemistry and materials science.

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What is gold-catalyzed cyclo-isomerization of 16-diyne-4-en-3-ols?

Gold-catalyzed cyclo-isomerization of 16-diyne-4-en-3-ols is a chemical reaction that converts the starting material into a cyclic compound using gold as a catalyst.

Who is required to file gold-catalyzed cyclo-isomerization of 16-diyne-4-en-3-ols?

Researchers and scientists conducting experiments or studies involving gold-catalyzed cyclo-isomerization of 16-diyne-4-en-3-ols are required to report their findings and results.

How to fill out gold-catalyzed cyclo-isomerization of 16-diyne-4-en-3-ols?

To fill out the gold-catalyzed cyclo-isomerization of 16-diyne-4-en-3-ols, one must provide detailed information about the reaction conditions, starting materials, catalyst used, and the obtained product.

What is the purpose of gold-catalyzed cyclo-isomerization of 16-diyne-4-en-3-ols?

The purpose of gold-catalyzed cyclo-isomerization of 16-diyne-4-en-3-ols is to efficiently synthesize cyclic compounds with specific stereochemical properties.

What information must be reported on gold-catalyzed cyclo-isomerization of 16-diyne-4-en-3-ols?

The information that must be reported includes the reaction conditions, characterization data of the product, yield, and any unexpected observations or side reactions.

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