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Supplementary material The following material accompanies the article Comparative efficacy and acceptability of nonsurgical brain stimulation in adult major depressive episodes: Systematic review
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01
Identify the interventions or treatments you want to compare.
02
Gather quantitative data on the effectiveness of each intervention.
03
Collect data on the acceptability of each treatment, including patient satisfaction and adherence.
04
Use a standardized format to report the comparative efficacy results, including relevant statistical analyses.
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Outline the criteria for acceptability and present the data in a clear manner, such as graphs or tables.
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Discuss the implications of your findings for different stakeholders.

Who needs comparative efficacy and acceptability?

01
Healthcare providers seeking to choose between treatment options.
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Pharmaceutical companies looking to market their products against competitors.
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Comparative efficacy refers to the effectiveness of a treatment compared to another treatment or standard. Acceptability pertains to the willingness of patients or healthcare providers to use a treatment based on its benefits, side effects, and overall convenience.
Typically, pharmaceutical companies, medical researchers, and healthcare organizations conducting clinical trials or research studies are required to file comparative efficacy and acceptability data.
To fill out comparative efficacy and acceptability, one should gather relevant data from clinical trials, summarize the results comparing the efficacy of treatments, and assess patient and provider feedback to evaluate acceptability before submitting the documentation to the appropriate regulatory body.
The purpose of comparative efficacy and acceptability is to provide evidence for healthcare decisions, support regulatory approvals, and guide clinical practice by demonstrating how a treatment performs relative to others in terms of effectiveness and user satisfaction.
Information that must be reported includes study design, population details, outcome measures, statistical analyses, efficacy results, acceptability feedback, adverse effects, and any limitations of the findings.
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