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Review published: 26 May 2017 doi: 10.3389/fimmu.2017.00605Regulatory T Cell and Forkhead Box Protein 3 as Modulators of immune Homeostasis Leonn Mendes Soares Pereira1,2, Samara Tatielle Monteiro
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Regulatory T cells, also known as Tregs, are a specialized subpopulation of T cells that play a crucial role in maintaining immune tolerance and preventing autoimmune responses by suppressing the activity of other immune cells.
Typically, researchers, healthcare providers, or pharmaceutical companies involved in clinical trials or studies related to T cell therapies may be required to report regulatory T cell data to regulatory authorities.
To fill out regulatory T cell documentation, one should provide detailed information about the study design, methodology, specimen collection, T cell characterization, and analysis results, ensuring compliance with regulatory guidelines.
The purpose of regulatory T cell documentation is to ensure that the usage of Tregs in therapeutic applications is safe and effective, and that it adheres to regulatory standards to protect patient health.
Information that must be reported includes patient demographics, T cell isolation methods, functional assays, efficacy results, safety data, and any adverse events associated with the therapy.
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