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Phase 0. Phase 0 trials are the first clinical trials done among people. Phase I. Phase I trials aim to find the best dose of a new drug with the fewest side effects. Phase II. Phase II trials further assess safety as well as if a drug works. Phase III. Phase IV.
A Clinical Trials Application (CTA) is the application/submission to the competent National. Regulatory Authority(ies) for authorization to conduct a clinical trial in a specific country.
For example, a clinical trial could involve new drugs, medical devices, biologicals, vaccines, surgical and other medical treatments and procedures. Psycho-therapeutic and behavioural therapies help service changes, preventative care strategies and educational interventions are also examples of clinical trials.
A clinical research associate (CRA) is a health care or life sciences professional who oversees clinical trials on behalf of pharmaceutical companies, medical research institutes and government agencies. They are sometimes called clinical monitors or trial monitors.