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Directory Results for Identification of Novel Candidate Genes for Familial Thyroid Cancer by Whole Exome Sequencing. Thyroid carcinoma (TC) can be classified as medullary (MTC) and non-medullary (NMTC). While most TCs are sporadic, familial s of MTC and NMTC also exis to Identification of Novel Cathepsin B Inhibitors with Implications in Alzheimers Disease. Amyloid precursor protein (APP), upon proteolytic degradation, s aggregates of amyloid(A) and plaques in the brain, which are pathological hallmarks of Alzhei