Last updated on
Sep 27, 2025
21 CFR Part 11 compliant PDF Software for NPO
Digitize your document workflows and improve collaboration between departments with comprehensive PDF software. Get access to an online PDF editor, fillable forms, secure sharing, and advanced eSignature workflows.
Learn how pdfFiller makes your work easier
Master pdfFiller in less than ten minutes.An intuitive UI and easy-to-use features make using pdfFiller quick and easy.
PDF editing from anywhere – desktop, web, or mobile
Fill out, edit, and annotate PDFs online on any device. Manage pages and add fillable fields and watermarks anywhere on a PDF.
Online PDF converter
Save your edited PDF as a Word document, Excel Spreadsheet, PowerPoint presentation, or JPEG image.
Advanced security
Restrict access to your PDFs with a password, save sensitive documents to an encrypted folder, and require document recipients to authenticate their identity.
Built-in export options
Send documents to stakeholders via email, SMS, or fax. Select a format, personalize your message, and set notifications before sending.
Document organization
Add tags to documents to simplify organization. Create unlimited folders and subfolders in your account.
Real-time collaboration
Share documents and folders with teammates for secure collaboration. Set up access permissions to prevent unwanted changes.
Seamless eSignature workflows
Send PDF documents for signature in a role-based order using signNow. Track the signing status of documents in real-time.
Integration with cloud storage services
Connect your favorite cloud storage to pdfFiller to instantly import documents to your account and save them in the cloud.
Custom branding
Make your documents and invitations recognizable by adding your company logo and business cards.
Don’t take our word for it, pdfFiller has won multiple awards
4.6/5
— from 710 reviews
pdfFiller users from small and large companies are weighing in
21 CFR Part 11 compliant PDF Software for NPO
Start saving time and money on your document routines right now.
You have a small team but want to make its workflows digital?
We’ve created a Premium subscription specifically for teams of 1-5 users. Premium is packed with everything pdfFiller has to offer, plus full-featured eSignatures. Check it out and Start free trial on the spot.
pdfFiller is the best one-stop-shop for your document workflows
See how our solution beats the competition.
This chart represents a partial list of features available in pdfFiller, DocuSign, Adobe Acrobat and PandaDoc
DocuSign
Adobe Acrobat
PandaDoc
General
Host Fillable Forms
Templates
PDF Converter
Merge PDF
Create documents and forms
Collect Payments
Notarize
Send to IRS
Sell forms
Fill in multiple forms at once
Postfill and bulk extract
Reminders
Audit Trail
Referral program
Security
Protect PDF
Encrypted folders
2FA
eSign
eSign
In-person signing
Editor
Edit PDF
Add Fillable Fields
Magic fields
Conditional fields
Field validation
Collaboration
Additional accounts
Applications
iOS
Android
MacOS
Windows
Offline mode on mobile
Enterprise
Premium support, dedicated assistant
API
Intergations
Compliance
PCI DSS certification
GDPR compliance
SOC2
21 CFR part 11
HIPAA compliance
Sign-in options
Google
Facebook
Apple
Everything you need to digitize document workflows at the market’s lowest price
pdfFiller includes tools and features normally sold separately and at a much higher price. With the Basic annual plan, you pay just $96 for the same set of features and save big.
Powerful PDF editor
Fillable forms
eSignature
$96
/year
DocuSign
eSignature
$120
/year
Adobe Acrobat
PDF editor
Fillable forms
$179.88
/year
PandaDoc
PDF editor
Fillable forms
eSignature
$228
/year
Industry-leading compliance
pdfFiller helps your company maintain compliance with global laws and regulations such as HIPAA, GDPR, PCI DSS, SOC 2 Type 2.
HIPAA compliance
Protects the private health information of your patients.
GDPR compliance
Regulates the use and holding of personal data belonging to EU residents.
SOC 2 Type II Certified
Guarantees the security of your data & the privacy of your clients.
CCPA compliance
Enhances the protection of personal data and the privacy of California residents.
The 21 CFR Part 11 compliant PDF Software for NPO for your company
A great way to enhance the effectiveness of your organization is to digitalize its document workflows. Creating, modifying, approving, and storing forms - all of these can be accomplished with the help of a single tool.
The 21 CFR Part 11 compliant PDF Software for NPO and other business tools
21 CFR Part 11 compliant PDF Software for NPO can substantially ease the process of document management! This kind of software for your forms will not only minimize the expenses associated with printing, scanning, and shipping papers but will also save the time your team spends on handling paperwork. It additionally gives better opportunities to collaborate on forms as a team with 24/7 online access from any device.
Sharing documents becomes simpler and the time needed to process them is decreased. You can also easily monitor alterations made to each record at any time in the process. In addition, when it comes to storing files with the cloud services included, you can be certain that your data is safe and cannot be lost, unlike with physical papers.
pdfFiller for Enterprise vs. other solutions
pdfFiller provides an all-in-one solution for enterprises that want to simplify their document workflows. The service supports various file types and enables you to convert documents to other formats. It will be helpful for data collection, form creation, tax filing, as well as PDF editing itself. Built-in eSignature capabilities ensure that your documents will have the same legal status as if they had a handwritten signature.
pdfFiller complies with the highest security criteria, implementing the encryption algorithm employed in the banking and healthcare industries. Hence, you can use the 21 CFR Part 11 compliant PDF Software for NPO functions without the risk of data loss.
Contact pdfFiller’s customer support to discover how your company can take advantage of pdfFiller for Enterprise.
Choose the best PDF editing software
Cloud-based
10x more powerful
50% lower cost
Easy to use
Legacy PDF editors
Expensive
Less functionality
Inefficient collaboration
Not mobile-friendly