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The variety of choices in editing is more than adequit it is awesome.
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That I do not know enough about all the features
What problems are you solving with the product? What benefits have you realized?
complex documents of contracts are easily modified
2019-05-22
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2020-09-25
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What is a processed transcript?
A processed transcript is a noncoding transcript that does not contain an open reading frame (OF). This type of transcript is annotated by VEGA/Havana.
What does transcript variant mean?
Isoforms refers to different versions of protein from the same gene in this setting, and transcript variants refers to different versions of mRNA transcript from the same gene. ADD COMMENT link written 4.7 years ago by wangyi2412 220.
What are isoform?
Medical Definition of isoform : any of two or more functionally similar proteins that have a similar but not identical amino acid sequence and are either encoded by different genes or by RNA transcripts from the same gene which have had different exons removed.
What is an isoform of a protein?
A protein isoform is one of a number of different structurally similar proteins that are created as the result of alternative splicing or from similar genes formed from a copied gene and differentiated as the result of evolution.
What is a splice isoform?
Alternative splicing (AS) therefore is a process by which exons or portions of exons or noncoding regions within a pre-mRNA transcript are differentially joined or skipped, resulting in multiple protein isoforms being encoded by a single gene.
What is a canonical sequence?
A canonical sequence is a sequence of DNA, RNA, or amino acids that reflects the most common choice of base or amino acid at each position.
How can a single gene produce multiple proteins?
Alternative splicing, or differential splicing, is a regulated process during gene expression that results in a single gene coding for multiple proteins. In this process, particular exons of a gene may be included within or excluded from the final, processed messenger RNA (mRNA) produced from that gene.
What is the benefit of alternative splicing?
The overall function of alternative splicing is to increase the diversity of the mRNA expressed from the genome. Due to the combinatorial control mechanisms that regulate alternative exon recognition, splicing programs coordinate the generation of mRNA isoforms from multiple genes.
What is an advantage of alternative splicing?
This has several advantages: (i) it allows a high sequence flexibility of exotic regulatory sequences that puts no constrains on coding requirements, (ii) the protein interaction can be influenced by small changes in the concentration of regulatory proteins which allows the alternative usage of exons depending on a ...
What is the purpose of alternative splicing in eukaryotic cells?
Alternative splicing (AS) therefore is a process by which exons or portions of exons or noncoding regions within a pre-mRNA transcript are differentially joined or skipped, resulting in multiple protein isoforms being encoded by a single gene.
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