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Cumulative percentage release (%) = Volume of sample withdrawn (ml)/bath volume (v) × P (t 1) + Pt. Where Pt = Percentage release at time t. Where P (t 1) = Percentage release previous to't'
d = thickness of the concentration gradient (m) Cs = particle surface (saturation) concentration (kg or moles/L) Cb = concentration in the bulk solvent/solution (kg or moles/L). Solubility is an endpoint representing dissolution capacity. Dissolution rate can be expressed using the Noyes Whitney equation.
Next, you need to calculate the Cumulative Percentage, in cell D4 for example, input this formula =C4/$C$11, (the cell C4 indicates the number of the first complaints, and the cell C11 contains the total number of the complaints) and then drag the formula down to fill the range you want to use.
Cumulative percentage release (%) = Volume of sample withdrawn (ml)/bath volume (v) × P (t 1) + Pt. Where Pt = Percentage release at time t. Where P (t 1) = Percentage release previous to't'
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