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Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release [ER, XR, XL] dosage) or to a specific target in the body (targeted-release dosage).
While prolonged release tablets are meant to effect after some time from the moment they are administered, and they are known to be released in small portions over a long period of time with no specifications to time or rate of concentration. Sustained release tablets are more of a controlled release.
Definition of 'prolonged-release' Prolonged-release drugs release the active ingredients slowly and work for a longer time. A prolonged-release drug delivers a dose of a medication over an extended period of time.
All Answers (14) Sustained release dosage forms are designed to release a drug at a predetermined rate in order to maintain a constant drug concentration for a specific period of time with minimum side effects. Sustained release's definition is more akin to a “controlled release” rather than “sustained”.
Extended-release means the pill is formulated so that the drug is released slowly over time. This has the advantage of taking pills less often. It also means that there may be fewer side effects as the levels of the of drug in the body are more consistent in extended- release formulations.
Controlled dosage forms contain methods to promote localization of the drug at active site. Zero order release that is the drug release over time irrespective of concentration. Sustained release implies slow release of the drug over a time period. It may or may not be controlled release.
Sustained Release Drug Delivery System (SRD DS) is designed to release a drug at a predetermined rate by maintaining a constant drug level for a specific period of time with minimum side effects. SR of drugs in GI tract following oral administration is not affected by the absorption process.
Definition of 'controlled-release' A controlled-release drug or preparation is released into the body in specified amounts over a specified period of time. The controlled-release system is designed to release the drug's active ingredient gradually over the day.
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