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These genes are APC ATM BAP1 BARD1 BMPR1A BRCA1 BRCA2 BRIP1 CDH1 CDK4 CDKN2A p14ARF and p16INK4a CHEK2 EPCAM GREM1 MITF MLH1 MSH2 MSH6 MUTYH NBN PALB2 PMS2 POLD1 POLE PTEN RAD51C RAD51D SMAD4 STK11 and TP53. 0/. Accessed April 2015. 29. Walsh T Casadei S Coats KH et al. Spectrum of mutations in BRCA1 BRCA2 CHEK2 and TP53 in families at high risk of breast cancer. 25. FDA Standards for NGS. FDA Developing Analytical www. fda.gov/downloads/MedicalDevices/NewsEvents/...
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How to fill out hereditary cancer genetic test

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How to Fill Out Hereditary Cancer Genetic Test:

01
Start by gathering the necessary materials for the test, which typically include a saliva or blood collection kit provided by the genetic testing company. Ensure that the kit is not expired and that all components are intact.
02
Carefully read the instructions provided with the kit. Familiarize yourself with the steps involved in collecting the sample, including any specific instructions on fasting or medication restrictions before the test.
03
If it is a saliva collection kit, refrain from eating, drinking, smoking, or brushing your teeth for at least 30 minutes prior to providing the sample. Open the saliva collection tube carefully without touching the inside, and spit into the tube until it reaches the required fill line. Follow any additional instructions on how to properly seal and label the sample.
04
If it is a blood collection kit, clean the area of the puncture site with an alcohol swab for sterilization. Use the provided lancet to prick your finger or follow any other specific instructions. Apply firm pressure to the puncture site to allow blood to flow into the collection container. Again, ensure that the container is properly sealed and labeled.
05
Fill out any required paperwork or forms provided by the genetic testing company. This may include providing personal information such as name, age, gender, and contact details. Read and answer any questionnaires or consent forms accurately and thoroughly.
06
Follow the specific instructions on how to return the sample to the genetic testing company. This typically involves placing the sealed sample container into a provided return envelope or box. Make sure to include any required paperwork or consent forms before sealing the envelope or box.

Who needs hereditary cancer genetic test:

01
Individuals with a significant family history of certain types of cancer, such as breast, ovarian, colorectal, or prostate cancer, may consider undergoing a hereditary cancer genetic test. This can help determine their risk of developing these cancers and guide appropriate preventive measures.
02
People who have already been diagnosed with cancer may choose to undergo a hereditary cancer genetic test to understand if their cancer is hereditary and assess the risk of developing additional cancers in the future.
03
Individuals who have a known genetic mutation in their family, such as BRCA1 or BRCA2, may opt for a hereditary cancer genetic test to determine if they have inherited the mutation and assess their cancer risk.
04
Certain ethnic or racial groups may have a higher prevalence of specific genetic mutations linked to hereditary cancer. Therefore, individuals belonging to these populations may consider a hereditary cancer genetic test to assess their risk more accurately.
05
Healthcare providers may recommend a hereditary cancer genetic test based on an individual's personal and medical history, especially if there are indicators that suggest a higher likelihood of an inherited cancer syndrome.
It is important to consult with a healthcare professional, such as a genetic counselor, to discuss your personal situation and determine if a hereditary cancer genetic test is appropriate for you.
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A hereditary cancer genetic test is a test that looks for specific inherited mutations (changes) in a person's genes that are associated with an increased risk of developing cancer.
Individuals with a family history of cancer or those who have been diagnosed with certain types of cancer may be required or recommended to undergo hereditary cancer genetic testing.
Hereditary cancer genetic tests are usually performed by collecting a blood or saliva sample from the individual and sending it to a specialized laboratory for analysis.
The purpose of hereditary cancer genetic testing is to help identify individuals who may have an increased risk of developing certain types of cancer, allowing for personalized screening and preventive measures.
The report from a hereditary cancer genetic test typically includes information on specific genetic mutations found, as well as an assessment of the individual's overall cancer risk.
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