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Histopathology and CytologyIHistopathology and Cytology Laboratory1Contact Information6/F, Public Health Laboratory Center, 382 Nam Cheng Street, She Kip Ma, Kowloon. 8:42am 5:30pm (Mon Fri); 9:00am
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01
Carefully review the sample: Start by thoroughly examining the sample provided for histopathology and cytology. Ensure that the sample is correctly labeled and that it includes all necessary information.
02
Prepare the slides: For histopathology, take the sample and prepare thin sections, typically around 4-5 micrometers thick. These sections should be mounted on glass slides and dried properly before further processing. For cytology, samples are typically obtained through fine needle aspiration or exfoliative methods and are directly smeared onto glass slides.
03
Stain the slides: Histopathology slides are commonly stained with hematoxylin and eosin (H&E) to enhance the visualization of tissue components. Follow proper staining protocols and ensure that the slides are properly dehydrated, cleared, and coverslipped once staining is complete. Cytology slides can be stained with a variety of methods, including Romanowsky stains like Diff-Quik or Papanicolaou stains such as the Pap stain.
04
Microscopic examination: Once the slides are prepared and stained, carefully examine them under a microscope. Observe the cellular morphology, tissue architecture, and any anomalies present. Document your findings with detailed descriptions and/or illustrations.
05
Diagnosis and interpretation: Based on the observations made during microscopic examination, make a diagnosis and interpret the histopathological or cytological findings. This may involve identifying abnormal cellular characteristics, detecting cancerous or infectious agents, or evaluating the presence of specific markers.
06
Reporting: After reaching a diagnosis, it is crucial to accurately and concisely report your findings. Prepare a comprehensive report that includes relevant clinical information, the microscopic description, diagnosis, and any additional recommendations or comments.

Who needs histopathology and cytology?

01
Medical professionals: Histopathology and cytology are essential diagnostic tools for medical professionals, including pathologists, cytotechnologists, and clinicians. They rely on these techniques to accurately diagnose and manage various diseases, such as cancer, infections, autoimmune disorders, and many others.
02
Researchers: Histopathology and cytology techniques are also widely utilized in research. Scientists use these methods to study disease mechanisms, evaluate the efficacy of new drugs or treatments, and investigate cellular and tissue changes during various biological processes.
03
Veterinary professionals: Histopathology and cytology are not limited to human medicine. Veterinary professionals also rely on these techniques to diagnose and manage diseases in animals, both in clinical practice and research settings.
04
Forensic experts: Histopathology and cytology play a crucial role in forensic investigations. These techniques help forensic pathologists and scientists determine the cause and manner of death, identify injuries or toxins, and provide valuable evidence in criminal cases.
05
Biopsy and cancer screening centers: Histopathology and cytology are commonly performed in biopsy and cancer screening centers. These facilities collect and process samples from patients to accurately diagnose various types of cancers, monitor disease progression, and guide treatment decisions.
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Histopathology is the examination of tissue samples under a microscope to study the changes in tissues caused by disease. Cytology is the study of individual cells to diagnose diseases.
Histopathology and cytology reports are typically filed by pathologists or medical professionals who analyze tissue or cell samples.
Histopathology and cytology reports are filled out by documenting observations, interpretations, and findings from analyzing tissue or cell samples.
The purpose of histopathology and cytology is to diagnose diseases, determine the nature of tumors, and monitor the effectiveness of treatments.
Histopathology and cytology reports typically include patient information, sample details, observations, interpretations, and diagnostic conclusions.
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