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The document details the characteristics, variations, and abnormalities of red blood cells (erythrocytes) through evaluations of slides, focusing on size, color, shape, inclusions, and distribution,
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How to fill out Morphologic Abnormalities of the Erythrocyte

01
Collect a blood sample from the patient using sterile techniques.
02
Prepare a thin blood smear on a glass microscope slide.
03
Allow the smear to air dry completely.
04
Fix the smear using methanol or another fixative for a specified time.
05
Stain the slide with a suitable stain (e.g., Wright's stain or Giemsa stain) to visualize the erythrocytes.
06
Examine the stained slide under a microscope at different magnifications.
07
Identify and note any abnormalities in the shape, size, or color of the erythrocytes.
08
Record your observations using standardized terms for abnormalities (e.g., anisocytosis, poikilocytosis).
09
Compile findings into a report, including relevant details such as the patient's clinical background.

Who needs Morphologic Abnormalities of the Erythrocyte?

01
Patients with anemia or unexplained fatigue.
02
Individuals undergoing routine blood tests for health screening.
03
Patients with a history of blood disorders.
04
Individuals suspected of having hemolytic anemia or other hematological conditions.
05
Healthcare professionals seeking to diagnose or manage blood-related diseases.
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People Also Ask about

Problems with erythropoiesis may cause you to have too few red blood cells (anemia) or too many red blood cells (erythrocytosis). Anemia: You don't have enough red blood cells to carry oxygen to your body's tissues. As a result, you may feel weak, tired or cold. There are different types of anemia.
Poikilocytosis refers to an increase in abnormal red blood cells of any shape that makes up 10% or more of the total population. Poikilocytes can be flat, elongated, teardrop-shaped, crescent-shaped, sickle-shaped, or can have pointy or thorn-like projections, or may have other abnormal features.
Primary abnormalities of the erythrocyte membrane lead to a variety of clinical syndromes including hereditary spherocytosis, hereditary elliptocytosis, and related disorders. Clinical and laboratory manifestations, as well as associated molecular defects, of these disorders vary widely.
Red cell morphology may be altered by alterations in lipid, iron and oxidative metabolism, immune-mediated disease, mechanical fragmentation, and by electrolyte or metabolic abnormalities. Most shape changes result from alteration of the red cell membrane.
As regards to RBCs morphology, a number of abnormalities have been described, including polichromasia, basophilic stippling, rouleaux, auto-agglutination, spherocytes, schistocytes, stomatocytes, knizocytes, and mushroom-shaped cells (Berzuini et al., 2021; Gerard et al., 2021), usually without association with
Common causes of abnormal red blood cells include: Drepanocytes (sickle cells): sickle cell disease. ‌Spherocytes (sphere or round-shaped): autoimmune disorders, transfusion reactions, diseases of newborns, or snakebites. ‌Dacrocytes (teardrop cells): leukemia, megaloblastic anemia, or myelofibrosis.
Normally, a person's RBCs (also called erythrocytes) are disk-shaped with a flattened center on both sides. Essentially, an abnormal RBC T morphology just means that you have abnormally shaped red blood cells present in your blood. Not an abnormal finding for the diagnosis and can be related to anemia.
A higher than normal number of RBCs in the may be due to: Kidney and other urinary tract problems, such as infection, or stones. Kidney inflammation or injury. Prostate problems. Bladder, kidney, or urinary tract cancer.

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Morphologic abnormalities of the erythrocyte refer to structural alterations in red blood cells that can affect their shape, size, and appearance, potentially indicating various underlying health issues.
Healthcare professionals, particularly those in hematology, pathologists, and laboratory technicians, are required to file reports on morphologic abnormalities of erythrocytes for diagnostic purposes.
To fill out a report on morphologic abnormalities of the erythrocyte, one must gather patient blood smear data, describe the observed abnormalities, include any relevant clinical data, and provide a summary or interpretation of findings.
The purpose of documenting morphologic abnormalities of the erythrocyte is to aid in the diagnosis of various hematological diseases, monitor disease progress, and guide treatment decisions.
The report must include the type of abnormalities observed (e.g., anisocytosis, poikilocytosis), percentage of abnormal erythrocytes, patient demographic information, clinical history, and any interpretative comments.
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