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This document provides guidelines and procedures to prevent and treat extravasation of chemotherapeutic agents in patients, detailing the recognition, prevention, and management of such events.
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How to fill out Extravasation Procedure for Chemotherapeutic Agents

01
Gather all necessary materials and equipment for the procedure.
02
Identify the patient and confirm the chemotherapy treatment plan.
03
Explain the procedure to the patient and obtain informed consent.
04
Prepare the medication as per standard protocols.
05
Choose an appropriate vein for IV access and cleanse the site.
06
Insert the IV catheter and ensure proper placement by aspirating for blood return.
07
Administer the chemotherapeutic agent slowly, monitoring the site for any signs of extravasation.
08
If extravasation occurs, stop the infusion immediately.
09
Follow the protocol for extravasation management, which may include using cold or warm packs and administering antidotes.
10
Document the incident thoroughly in the patient's medical record.

Who needs Extravasation Procedure for Chemotherapeutic Agents?

01
Patients receiving chemotherapeutic agents intravenously, especially those with a high risk of extravasation due to specific medications or pre-existing conditions.
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At the first sign of extravasation, nursing intervention with following steps is recommended: stop administration of IV fluids immediately, disconnect the IV tube from the cannula, aspirate any remaining drug from the cannula, administer drug-specific antidote, and notify the physician.
Warm compresses are preferred for extravasation of specific drugs including vinca alkaloids, etoposide, vasopressors, and oxaliplatin to increase local blood flow and enhance drug removal. Apply compresses for 20 to 60 minutes 3 or 4 times daily for the first 24 to 72 hours after extravasation occurs.
Treatment Stop infusion. Do not remove IV line. Elevate affected limb if possible. Do not flush the line. Attempt aspiration of remaining drug from IV line with a small syringe. Administer pain relief if required. Assess extent of swelling and type of drug/fluid (above), and use table below to guide management.
If extravasation does occur Immediately stop the infusion and disconnect the tubing as close to the catheter hub as possible. Attach a syringe to the hub and attempt to aspirate the remaining drug from the catheter. Estimate the amount of extravasated solution and notify the healthcare provider.
Apply dry warm compresses for 20–30 min at a time, 4 times a day for the first 24–48 hr following extravasation.
At the first sign of extravasation, the following steps are recommended: (1) stop administration of IV fluids immediately, (2) disconnect the IV tube from the cannula, (3) aspirate any residual drug from the cannula, (4) administer a drug-specific antidote, and (5) notify the physician (Fig.
At the first sign of extravasation, the following steps are recommended: (1) stop administration of IV fluids immediately, (2) disconnect the IV tube from the cannula, (3) aspirate any residual drug from the cannula, (4) administer a drug-specific antidote, and (5) notify the physician (Fig. 1).

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The Extravasation Procedure for Chemotherapeutic Agents is a set of guidelines and protocols designed to manage and mitigate the effects of chemotherapy agents that inadvertently leak into the surrounding tissue during administration.
Healthcare professionals involved in the administration of chemotherapeutic agents, such as nurses and oncologists, are required to file the Extravasation Procedure following an incident of extravasation.
To fill out the Extravasation Procedure, the healthcare provider should document the patient’s details, the drug involved, the date and time of the incident, specific observations regarding the extravasation, interventions taken, and any follow-up steps required.
The purpose of the Extravasation Procedure is to ensure timely recognition and intervention to minimize tissue damage and complications associated with the leakage of chemotherapeutic agents.
The information that must be reported includes the patient's name and identification, the specific chemotherapeutic agent involved, the date and time of the incident, assessment findings, treatment given, and any further instructions for patient care.
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