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This document is used for submitting research grant applications to the Public Health Service, including details about the project title, principal investigator, human subjects involvement, budget,
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How to fill out PHS 398

01
Download the PHS 398 form from the official NIH website.
02
Read the instructions carefully to understand the requirements for each section.
03
Fill out the title page with your project title, applicant organization, and principal investigator details.
04
Complete the project summary and relevance section, outlining the goals and significance of your research.
05
Fill in the research strategy section, detailing your approach, methodology, and anticipated outcomes.
06
Include the budget and budget justification, specifying how funds will be used in your project.
07
Attach the necessary biosketches for key personnel involved in the project.
08
Review the entire application for completeness and accuracy before submission.
09
Submit the completed PHS 398 form through the appropriate NIH submission portal.

Who needs PHS 398?

01
Researchers applying for NIH grants.
02
Academic institutions seeking funding for scientific research projects.
03
Non-profit organizations involved in health-related research.
04
Individuals conducting studies relevant to public health.
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People Also Ask about

A research plan is pivotal to a research project because it identifies and helps define your focus, method, and goals while also outlining the research project from start to finish. This type of plan is often necessary to: Apply for grants or internal company funding.
This Policy applies to all research funded or proposed for funding by the Public Health Service of the U.S. Department of Health and Human Services (“PHS”), including the National Institutes of Health (“NIH”).
The PHS 398 Research Training Program Plan Form is used only for Training applications and Multi-project applications with an "NRSA Training" Component. This form includes fields to upload several attachments including the Program Plan, Faculty Biosketches, and Data Tables.
The PHS 398 Research Plan form is used only for research, multi-project, and SBIR/STTR applications. This form includes fields to upload several attachments, including the Specific Aims and Research Strategy.
While SROs do not make decisions about funding, their summary statements are sent to program officers whose next stage of peer review leads to funding decisions made by other branches of the NIH. “I spend a lot of time going through their critiques,” Szymczyk said.
The PHS Policy, frequently referred to as the NIH Policy, requires each institution receiving PHS funds for research involving animals to submit detailed information regarding the institution's program for the care and use of animals (including farm animals, mice, and rats) to the Office of Laboratory Animal Welfare (

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PHS 398 is a form used by the Public Health Service (PHS) to apply for research grants and cooperative agreements. It standardizes the application process for various funding opportunities.
Any institution or individual seeking funding from the PHS for research projects is required to file PHS 398.
PHS 398 can be filled out by following specific instructions provided in the application guide. Applicants must provide detailed information about the research project, including objectives, methodology, and budget.
The purpose of PHS 398 is to gather comprehensive information about proposed research projects to assess their merit and potential impact, thereby guiding funding decisions.
PHS 398 requires reporting information such as project title, abstract, specific aims, research design and methods, budget, and biographical sketches of key personnel.
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