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A publication for alumni and friends of the University of Missouri-St. Louis School of Optometry containing updates, faculty achievements, alumni news, and upcoming events.
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How to fill out eyewire - umsl

How to fill out EyeWire
01
Visit the EyeWire website and create an account.
02
Watch the tutorial to understand the gameplay and objectives.
03
Start a new game by clicking on the 'Start' button.
04
Use your mouse to trace the neural connections as prompted.
05
Submit your completed tracing for evaluation.
06
Review feedback and learn from any mistakes to improve your skills.
Who needs EyeWire?
01
Students and researchers in neuroscience looking to engage in citizen science.
02
Anyone interested in understanding brain structure and function.
03
Gamers who enjoy puzzle-solving and contributing to scientific research.
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What is the purpose of eyewire?
Eyewire gameplay is used for neuroscience research by enabling the reconstruction of morphological neuron data, which helps researchers model information-processing circuits. It is also used to generate a training dataset to further improve the artificial intelligence that assists the player through the gameplay.
How does eye wire work?
Players map branches of a neuron from one side of a cube to the other. They scroll through the cube and reconstruct neurons in segments with the help of an artificial intelligence (AI) algorithm, making connections that the AI missed. Multiple players map each cube; then their work is compared.
What has Eyewire accomplished so far?
It is a human-based computation game that uses players to map retinal neurons. Eyewire launched on December 10, 2012. The game utilizes data generated by the Max Planck Institute for Medical Research. As of March 2025, Eyewire has had around 350,000 players and resulted in the tracing of 6,000 neurons.
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What is EyeWire?
EyeWire is a project that involves crowdsourcing the mapping of the human brain by tracking the activity of neurons in the retina, helping to better understand how the brain processes visual information.
Who is required to file EyeWire?
Individuals or organizations involved in neuroscience research may be required to file EyeWire to contribute to the mapping of neural connections and to collaborate in data collection efforts.
How to fill out EyeWire?
To fill out EyeWire, participants must follow provided guidelines, which typically involve accurately tracing neuron paths as prompted by the EyeWire interface, ensuring all activity is submitted for review.
What is the purpose of EyeWire?
The purpose of EyeWire is to advance neuroscience by helping researchers understand the structure and function of the brain's neural networks, contributing to broader insights into brain functions.
What information must be reported on EyeWire?
Participants must report their tracing accuracy, submit completed neuron maps, and provide any additional required metadata associated with their contributions according to the project's protocols.
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