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Articles 2012 Nature America, Inc. All rights reserved. Large scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways Through
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Large-scale association analyses identify is a method used in statistics and genetics to investigate the relationships between genetic variants and phenotypic traits or diseases on a large scale. It involves analyzing large datasets, such as genome-wide association studies (GWAS) or other high-throughput genomics data, to identify genetic markers associated with specific traits or diseases.
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The specific information reported on large-scale association analyses identify depends on the dataset and research goals. However, typical information reported includes genetic variant information (e.g., SNP identifiers, chromosomal positions), phenotypic trait or disease information, statistical association measures (e.g., p-values, effect sizes), quality control metrics, and potentially covariate information (e.g., age, sex, population structure). The details of what to report can vary based on the guidelines or standards set by the relevant scientific community or publication requirements.
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