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This document outlines the procedures and agreements for transferring research materials from the University of Pennsylvania to recipient institutions for non-commercial research purposes.
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People Also Ask about

Epidemiology of AAV ANCA-associated vasculitides are rare conditions, affecting between 10 and 20 individuals per million people. GPA is the most common of the 3 main forms, affecting between 5 and 10 individuals per million people.
Adeno-associated virus. Adeno-associated viruses (AAV) are single stranded DNA viruses that have not been found to cause pathology in humans. The AAV is dependent on helper viruses for replication and for productive infection. AAV contains two genes, rep and cap, that are required for its replication.
Adeno-associated viruses (AAV) are small viruses that infect humans and some other primate species. They belong to the genus Dependoparvovirus, which in turn belongs to the family Parvoviridae.
Adeno-associated viruses (AAV) are small viruses that infect humans and some other primate species. They belong to the genus Dependoparvovirus, which in turn belongs to the family Parvoviridae.
More than 120 clinical trials using AAV have shown vector safety, with a transient and asymptomatic hepatitis as the most severe side effect. In comparison to the widespread use of AAV vectors in clinical, preclinical, and basic research, there has been limited study of the interaction of the parental virus in humans.
Simply put, AAV is a protein shell surrounding and protecting a small, single-stranded DNA genome of approximately 4.8 kilobases (kb). AAV belongs to the parvovirus family and is dependent on co-infection with other viruses, mainly adenoviruses, in order to replicate.
Adeno-associated virus (AAV) is a non-enveloped virus that can be engineered to deliver DNA to target cells, and has attracted a significant amount of attention in the field, especially in clinical-stage experimental therapeutic strategies.
Adeno-associated virus serotype 2 (AAV-2) is a replication-deficient parvovirus that infects humans, but produces no significant pathology (Blacklow et al., 1968a). The virus consists of a 5 kb single-stranded DNA genome, contained within a non-enveloped icosahedral capsid (Xie et al., 2002).

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A-OT AAV2/1 is a specific form used for reporting certain activities, requirements, or information related to a regulatory or compliance framework.
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