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This document outlines the guidelines for using the Elizabeth A. Rich Biosafety Level 3 Facility at the CWRU School of Medicine, detailing organization, procedures, equipment, biosafety practices,
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How to fill out GUIDELINES FOR USE OF THE ELIZABETH A. RICH BIOSAFETY LEVEL 3 FACILITY

01
Review the biosafety level 3 facility overview and safety protocols.
02
Gather the necessary documentation required for facility use.
03
Complete the application form for access to the facility.
04
Submit the application to the biosafety officer for approval.
05
Once approved, attend the mandatory training session on facility operations and safety procedures.
06
Familiarize yourself with the emergency procedures and equipment located in the facility.
07
Schedule your time for using the facility and ensure all safety measures are followed.
08
Maintain detailed records of materials and experiments conducted within the facility.

Who needs GUIDELINES FOR USE OF THE ELIZABETH A. RICH BIOSAFETY LEVEL 3 FACILITY?

01
Researchers working with potentially infectious agents.
02
Laboratory personnel handling biological samples in a high-containment environment.
03
Institutional biosafety committee members overseeing compliance.
04
Regulatory personnel monitoring biosafety practices.
05
Students involved in research projects requiring biosafety level 3 containment.
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Common safety controls within a BSL-3 lab include: The use of PPE, including goggles and gloves; respirators may also be required. The use of solid-front wraparound gowns, scrub suits, and/or coveralls is often required. Access to a hands-free sink and eyewash station available near the exit.
Biosafety guidelines are a set of policies, rules, and procedures that personnel in various facilities handling microbiological agents must follow. These agents include bacteria, viruses, parasites, fungi, prions, and other related microbial products.
Biosafety Level 3 (BSL-3) BSL-3 laboratories are designed to be easily decontaminated. As an additional safety measure, these laboratories must use controlled, or “directional,” air flow to ensure that air flows from non-laboratory areas (such as the hallway) into laboratory areas.
Biosafety guidelines are a set of policies, rules, and procedures that personnel in various facilities handling microbiological agents must follow. These agents include bacteria, viruses, parasites, fungi, prions, and other related microbial products.
Biosafety Level 3 Laboratories Adhering to general lab safety procedures, including donning and doffing PPE. Setting up, cleaning out, and properly using the biosafety cabinets. Bringing materials into and out of the biosafety cabinet.
The four biosafety levels are BSL-1, BSL-2, BSL-3, and BSL-4, with BSL-4 being the highest (maximum) level of containment. There are additional specific rules and designations for animal research (ABSL), agricultural research (BSL-Ag), and other types of research.
In the United States, the designations BSL-1, BSL-2, BSL-3, and BSL-4 describe the minimum safe work practices, specially designed buildings, and safety equipment required to conduct work on infectious microorganisms and other biological hazards.
Students may produce a written report that researchers and documents the 5 P's of Risk Assessment and Risk Management (Pathogen, Procedures, Protective Equipment, Personnel, and Place), from one of 10 sample situations.

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The GUIDELINES FOR USE OF THE ELIZABETH A. RICH BIOSAFETY LEVEL 3 FACILITY provide protocols and procedures designed to ensure the safe handling of pathogens and biological materials at biosafety level 3, protecting both personnel and the environment.
Researchers, laboratory personnel, and any individuals intending to use the Elizabeth A. Rich Biosafety Level 3 Facility are required to file the guidelines.
To fill out the guidelines, individuals must complete the provided forms detailing their research project, risk assessments, and biosafety protocols, and submit them to the appropriate institutional biosafety committee for review.
The purpose of these guidelines is to establish safe practices for working with infectious agents and to minimize risks to researchers and the surrounding community.
Information that must be reported includes the types of biological agents being used, the capabilities of the facility, risk assessments, training records, and emergency response plans.
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