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InvestigatorInitiated INDsMarjorie Small, RN, CCC Office of Clinical Research 23 May 2011 PHS/IRB Research Grand RoundsOutline of Presentation I. What is an IND?II. Code of Federal Regulations. When
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Start by gathering all necessary information and documents required for the application process. This may include the research proposal, budget information, CVs, and any supporting documents.
02
Carefully read and understand the guidelines and instructions provided by the funding agency or organization that offers investigator-initiated grants. It is crucial to follow these guidelines to ensure that your application meets all the requirements.
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Begin by filling out the basic information section of the application form, including your name, contact details, and affiliation. Double-check the accuracy of the provided information to avoid any mistakes.
04
Move on to the research proposal section. Clearly articulate the objectives, hypothesis, methodology, and significance of your proposed research. Provide a compelling rationale and justification for your project.
05
Pay close attention to the formatting and word limits specified in the application guidelines. Keep your writing concise, clear, and well-organized. Use headings, subheadings, and bullet points to make it easy for reviewers to navigate through your proposal.
06
If applicable, include a detailed budget section. Break down the anticipated expenses for the project, including personnel, supplies, equipment, and travel. Justify each item in the budget and ensure that it aligns with the scope and objectives of your research.
07
Make sure to address any special requirements or criteria specified by the funding agency, such as ethical considerations, collaborations, or data sharing plans. Provide any additional documents, such as consent forms or letters of support, as required.
08
Review and proofread your application multiple times to catch any errors or typos. Consider seeking feedback from colleagues or mentors to further improve the quality of your application.
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Submit the completed application before the designated deadline. Keep a copy of the application for your records.

Who needs investigator-initiated:

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Researchers who have an innovative research idea but lack dedicated funding can benefit from investigator-initiated grants. These grants allow researchers to propose and independently conduct their own research projects across various disciplines.
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Investigators who wish to explore new areas of research or pursue unconventional ideas that may not fit within the scope of traditional funding opportunities can find investigator-initiated grants valuable. These grants often offer researchers more flexibility and freedom to pursue their scientific curiosity.
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Institutions or organizations that support research and scientific advancement may offer investigator-initiated grants to foster innovation and promote independent research. These grants can help institutions attract talented researchers and advance knowledge in their respective fields.
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Investigator-initiated research is a study or project that is conceived and proposed by a researcher or investigator. It is not commissioned or initiated by a sponsor or external organization.
Investigators or researchers who propose and carry out the study are required to file investigator-initiated applications.
Investigators must follow the guidelines provided by the funding organization and complete all required sections of the application form.
The purpose of investigator-initiated research is to allow researchers to explore their own ideas and hypotheses, advancing knowledge in their field.
Investigators must report details about the study design, objectives, methods, anticipated outcomes, budget, and potential risks and benefits.
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