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This document outlines the clinical protocol for a phase 2 study evaluating the effectiveness and safety of TRC105 in treating recurrent or progressive glioblastoma after prior antiangiogenic therapy.
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IND 100522 is an investigational new drug application submitted to regulatory authorities to seek approval for a new drug's clinical trials.
Pharmaceutical companies or sponsors who wish to conduct clinical trials of a new drug must file IND 100522.
To fill out IND 100522, sponsors must provide comprehensive information including the drug's chemistry, pharmacology, and toxicology data, as well as a protocol for the clinical trials.
The purpose of IND 100522 is to ensure the safety and efficacy of the new drug before it can be tested in humans, thus protecting trial participants.
IND 100522 must report information on the drug's composition, manufacturing process, preclinical study results, proposed clinical trial protocols, and investigator qualifications.
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