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MOUSE GRIMACE SCALE (MGS): THE MANUAL I. VIDEO & FRAME CAPTURE PROCEDURES: Place mice individually in cubicles (9 × 5 × 5 cm high), with two walls of transparent Plexiglas and two opaque side walls
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How to fill out mouse grimace scale mgs
How to fill out mouse grimace scale (MGS):
01
Observe the mouse carefully: Look for any facial expressions or grimaces displayed by the mouse. This can include ear position, narrowing of the eyes, and changes in whisker position.
02
Assign a score: Use the MGS scoring system to assign a score to each facial feature observed. The scale typically ranges from 0 (no pain) to 2 (severe pain) for each feature, with a total possible score of 10.
03
Evaluate each feature: Assess the following facial features individually and assign a score accordingly:
3.1
Orbital tightening: Observe any tightening or narrowing of the area around the eyes.
3.2
Nose bulge: Look for any swelling or bulging of the nose.
3.3
Cheek bulge: Check for any bulging or swollen appearance of the cheeks.
3.4
Whisker change: Note any position changes or flattening of the whiskers.
3.5
Ear position: Observe any changes in the orientation or movement of the ears.
04
Calculate the total score: Add up the scores assigned to each facial feature to obtain the total MGS score for the mouse.
05
Keep records: Document the observed features and the corresponding scores for future reference and analysis. This can be done using a standardized data sheet or digital recording system.
Who needs the mouse grimace scale (MGS)?
01
Researchers: The MGS is often used by researchers in the field of animal welfare or pain assessment to evaluate pain responses in mice. It helps in understanding the impact of experimental procedures or interventions on the well-being of mice.
02
Veterinarians: Veterinarians may use the MGS as a tool to assess pain in mice, especially in clinical or laboratory settings. It aids in the diagnosis and treatment of various conditions that may cause discomfort in mice.
03
Animal care staff: Those responsible for the day-to-day care of mice, such as laboratory animal technicians or animal caretakers, may use the MGS for routine monitoring of pain levels in mice under their care. This tool helps ensure the welfare of the animals and facilitates prompt intervention if necessary.
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What is mouse grimace scale mgs?
Mouse Grimace Scale (MGS) is a method used to assess pain in mice by evaluating facial expressions and changes in behavior.
Who is required to file mouse grimace scale mgs?
Research laboratories, animal testing facilities, and institutions conducting studies on mice are required to use and file Mouse Grimace Scale (MGS) as part of their research protocols.
How to fill out mouse grimace scale mgs?
To fill out Mouse Grimace Scale (MGS), observers need to carefully evaluate the facial expressions of mice and score them based on predefined criteria.
What is the purpose of mouse grimace scale mgs?
The purpose of Mouse Grimace Scale (MGS) is to provide a standardized method for assessing pain in mice, which can help researchers and veterinarians in monitoring the welfare of animals in research settings.
What information must be reported on mouse grimace scale mgs?
The information reported on Mouse Grimace Scale (MGS) includes the scores given to facial expressions, changes in behavior, and assessment of pain levels in mice.
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