Get the free Platelet Refractoriness: Platelet Cross-Matching Requests - labmed ucsf

Platelet Refractories: Platelet CrossMatching Requests Platelet Transfusion Guidelines: Platelet products are generally in short supply in the UCSF hospital blood bank and at Blood Centers of the

How to fill out platelet refractoriness platelet cross-matching

How to fill out platelet refractoriness platelet cross-matching:

1. Gather all necessary information: Start by collecting all relevant data and information about the patient, such as their medical history, previous transfusions, and any known platelet antibodies.
2. Perform a clinical assessment: Evaluate the patient's clinical history, symptoms, and any signs of platelet refractoriness. This can help determine the need for cross-matching and guide further investigation.
3. Choose the appropriate testing method: There are different methods available for platelet cross-matching, such as solid-phase systems or gel-based techniques. Select the method that is suitable for your laboratory and financial resources.
4. Collect blood samples: Obtain the necessary blood samples from the patient and the potential platelet donors. Use proper venipuncture techniques and ensure appropriate sample handling to avoid any contamination or clot formation.
5. Determine the desired antigen compatibility: Identify the specific platelet antigens that are important for the patient, based on their previous transfusion history and known antibodies. This can guide the selection of the most compatible platelet unit.
6. Perform platelet cross-matching: Use the chosen testing method to assess the compatibility between the patient's serum and potential platelet units. Follow the manufacturer's instructions for the specific testing system used.
7. Interpret the results: Analyze the cross-matching results to determine the compatibility between the patient and potential platelets. Consider factors such as antibody presence, potency, and specific antigen match to assess the risk of platelet refractoriness.
8. Choose compatible platelet units: Based on the cross-matching results, select the platelet units that are most compatible with the patient's serum. Consult with the transfusion service or hematologist to make the final decision.

Who needs platelet refractoriness platelet cross-matching:

1. Patients with a history of platelet transfusion: Individuals who have previously received platelet transfusions may develop platelet refractoriness, which is a condition where the body becomes unresponsive to platelet transfusions. Platelet refractoriness can be caused by various factors, such as the development of platelet antibodies or a rapid platelet clearance rate.
2. Patients experiencing platelet transfusion failure: Platelet refractoriness should be considered in patients who do not show the expected response to platelet transfusions. This can manifest as a lack of improvement in platelet counts or an insufficient increase in platelet counts after transfusion.
3. Patients with specific medical conditions: Certain medical conditions, such as hematological malignancies, immune disorders, and solid organ transplant recipients, are associated with a higher risk of platelet refractoriness. These patients may require platelet cross-matching to identify compatible platelet units for transfusion.

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What is platelet refractoriness platelet cross-matching?

Platelet refractoriness platelet cross-matching is a laboratory procedure used to assess the compatibility between platelets from a donor and the recipient to determine if the recipient's immune system will accept the transfusion.

Who is required to file platelet refractoriness platelet cross-matching?

Platelet refractoriness platelet cross-matching is typically performed by medical professionals such as hematologists, blood bank technicians, or other healthcare workers involved in transfusion medicine.

How to fill out platelet refractoriness platelet cross-matching?

To fill out platelet refractoriness platelet cross-matching, specific information about the donor and recipient's blood types, HLA antigens, and previous transfusion history is required.

What is the purpose of platelet refractoriness platelet cross-matching?

The purpose of platelet refractoriness platelet cross-matching is to prevent adverse reactions in recipients who may have developed antibodies against platelets, making them refractory to transfusions.

What information must be reported on platelet refractoriness platelet cross-matching?

The results of platelet refractoriness platelet cross-matching should include compatibility testing, antibody screening, and any relevant medical history of the recipient.