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This document provides technical specifications for Rabbit Anti-DNA-PK Polyclonal Antibody, including details about its immunogen, species reactivity, applications, storage, safety data, and certification.

How to fill out anti-dna-pk

How to fill out Anti-DNA-PK

1. Gather all necessary materials, including the Anti-DNA-PK test kit.
2. Read the instructions provided with the test kit carefully.
3. Prepare your sample collection equipment, ensuring they are sterile.
4. Collect the blood sample as guided (usually through venipuncture).
5. Label the sample with the patient's information accurately.
6. Follow the specific steps for processing the sample as per the kit instructions.
7. Store the sample in the appropriate conditions until testing.
8. Complete any required documentation and send the sample to the lab.

Who needs Anti-DNA-PK?

1. Individuals with suspected autoimmune disorders.
2. Patients being evaluated for certain types of kidney disease.
3. Individuals with unexplained symptoms that may be linked to DNA damage.
4. Patients undergoing treatment for cancer who may need monitoring for DNA repair mechanisms.

People Also Ask about

What is anti-dsDNA in English?

Anti-double stranded DNA (anti-dsDNA) are antibodies that target double-stranded DNA molecules. The presence of anti-dsDNA serves as a marker for systemic lupus erythematosus (SLE) and autoimmune hepatitis, two chronic autoimmune disorders.

What is a DNA-PK inhibitor?

An orally bioavailable ATP-competitive inhibitor of the catalytic subunit of DNA-dependent protein kinase (DNA-PK), with potential sensitizing and enhancing activities for both chemo- and radiotherapies.

What does DNA-PK do?

Primarily, DNA-PK regulates repair of double strand breaks through the non-homologous end joining (NHEJ) DNA double strand break repair pathway (previously reviewed in depth [24]), a concept supported by the SCID phenotype of DNA-PKcs knockout mice resulting from lack of VDJ recombination during development [25].

What are DNA damage response inhibitors?

DNA damage response inhibitors are widely used anti-cancer agents that have potent activity against tumor cells with deficiencies in various DNA damage response proteins such as BRCA1/2.

What does DNA-PK do in NHEJ?

DNA-dependent protein kinase (DNA-PK), composed of Ku70, Ku80, and the catalytic subunit (DNA-PKcs), is involved in repairing double-strand breaks (DSBs) by nonhomologous end-joining (NHEJ). Certain proteins involved in NHEJ are also involved in DSB repair by homologous recombination (HR).

What is a PKA inhibitor?

PKA Inhibitors are essential tools for studying the function and regulation of protein kinase A (PKA), an enzyme that plays a crucial role in numerous cellular processes, including metabolism, gene expression, cell growth, and differentiation.

For pdfFiller’s FAQs

What is Anti-DNA-PK?

Anti-DNA-PK is a blood test that detects antibodies against DNA-dependent protein kinase, which is involved in DNA repair processes.

Who is required to file Anti-DNA-PK?

Individuals suspected of having autoimmune diseases, particularly systemic lupus erythematosus (SLE), may be required to file for the Anti-DNA-PK test.

How to fill out Anti-DNA-PK?

The Anti-DNA-PK test request form should be filled out with patient details, including personal information and clinical history, and must be submitted to a laboratory that performs the test.

What is the purpose of Anti-DNA-PK?

The purpose of the Anti-DNA-PK test is to diagnose autoimmune disorders, particularly to assess if a patient has systemic lupus erythematosus or similar conditions.

What information must be reported on Anti-DNA-PK?

The report for the Anti-DNA-PK test should include the patient's identification, the test results (presence of antibodies), reference ranges, and any relevant clinical interpretation.