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Downloaded from BMG.bmj.com on February 9, 2012, Published by group.bmj.com Journal of Medical Genetics 1985, 22, 182-186 Polymorphism of DNA sequence in the human pro u2(I) collagen gene A F GROBLER-RABIE,
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How to fill out polymorphism of DNA sequence in:

01
Start by obtaining the DNA sequence that you want to analyze for polymorphism. This could be a specific gene or a segment of the genome.
02
Use appropriate software or tools to align the DNA sequence with a reference sequence. This alignment helps in identifying any variations or differences in the DNA sequence.
03
Compare the aligned sequences and identify the polymorphic sites or regions where there are differences between the sequences.
04
Once the polymorphic sites have been identified, record the specific nucleotide changes or variations at these sites.
05
Analyze the frequency and distribution of the identified polymorphisms within the population or samples being studied.
06
Document the findings of the polymorphism analysis, including the specific nucleotide changes and their potential implications or significance.

Who needs polymorphism of DNA sequence in:

01
Researchers studying genetic variation and evolution use polymorphism analysis to understand the diversity of DNA sequences within and between populations.
02
Scientists studying diseases and their genetic causes may use polymorphism analysis to identify variations that could be associated with specific diseases or traits.
03
Geneticists and molecular biologists interested in studying gene function and regulation often utilize polymorphism analysis to investigate how differences in DNA sequences may affect gene expression or protein function.
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Polymorphism of DNA sequence refers to the presence of genetic variations in a population's DNA sequence.
Scientists, researchers, and geneticists studying genetic variations may be required to document and report polymorphism of DNA sequence.
To fill out a polymorphism of DNA sequence report, one would typically need to analyze DNA samples, identify genetic variations, and record the specific details of these variations in a standardized format.
The purpose of studying and reporting polymorphism of DNA sequence is to better understand the genetic diversity within a population, identify potential genetic markers for specific traits or diseases, and contribute to advancements in genetics research and applications.
The information reported on polymorphism of DNA sequence may include the specific genetic variations observed, their frequencies within the population, any phenotypic associations, and relevant metadata such as sample source and experimental methods.
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