Get the free Human Transforming Growth Factor β2 (hTGF-β2)

This document provides safety information for the product Human Transforming Growth Factor β2 (hTGF-β2), including its intended use, physical and chemical properties, hazard identification, first

How to fill out human transforming growth factor

How to fill out Human Transforming Growth Factor β2 (hTGF-β2)

1. Begin by gathering all necessary materials, including the hTGF-β2 assay kit and any required reagents.
2. Prepare the sample by diluting it according to the manufacturer's instructions, ensuring it is within the recommended range.
3. Set up your assay plate, adding the appropriate buffers or diluents to each well as specified.
4. Add the prepared sample to the designated wells, ensuring you have controls included for accuracy.
5. Follow the incubation times specified in the protocol for the reaction to occur.
6. After incubation, add any detection reagents required, such as antibodies that bind to hTGF-β2.
7. Incubate the plate again according to the kit instructions before adding substrate reagents.
8. Measure the optical density (OD) using a plate reader at the specified wavelength.
9. Analyze the data by comparing the OD readings against a standard curve to quantify hTGF-β2 levels.

Who needs Human Transforming Growth Factor β2 (hTGF-β2)?

1. Individuals undergoing diagnosis or monitoring of diseases where TGF-β2 is implicated, such as cancer or fibrosis.
2. Researchers studying the role of hTGF-β2 in various biological processes or disease mechanisms.
3. Clinicians evaluating therapeutic approaches related to disorders influenced by TGF-β2 levels.

People Also Ask about

What is the function of TGFB2?

The TGFB2 gene provides instructions for producing a protein called transforming growth factor beta-2 (TGFβ-2). This protein is found throughout the body and is required for development before birth and throughout life. To carry out its functions, TGFβ-2 attaches (binds) to receptor proteins on the surface of cells.

What is the role of TGF beta 2?

TGF beta 2 is defined as one of the isoforms of transforming growth factor beta, a homodimeric polypeptide involved in embryological development, connective tissue repair, and the regulation of extracellular matrix synthesis, particularly in the context of fibrosis and angiogenesis.

Is TGF-beta good or bad?

Transforming growth factor (TGF)-β is a multifunctional cytokine expressed by almost every tissue and cell type. The signal transduction of TGF-β can stimulate diverse cellular responses and is particularly critical to embryonic development, wound healing, tissue homeostasis, and immune homeostasis in health.

What does a high human transforming growth factor mean?

In the immune system, high TGF-β1 levels might suppress the body's ability to fight infections and tumors, potentially leading to an increased risk of certain cancers or chronic infections. Additionally, in autoimmune diseases, elevated TGF-β1 can contribute to the body's immune system attacking its own tissues.

What is the function of TGF-beta 2?

Because the TGFβ-2 protein keeps cells from growing and dividing too rapidly or in an uncontrolled way, it can suppress the formation of tumors. The TGFβ-2 protein plays a role in the formation of blood vessels, the regulation of muscle tissue and body fat development, wound healing, and immune system function.

What does TGF-β do?

TGFβ functions as a tumor suppressor by mediating its antiproliferative effects in a large variety of cell types. During early stages of tumorigenesis, TGFβ inhibits cell cycle promotion and evasion of TGFβ-mediated antiproliferative effects is a prerequisite for advancement of tumor progression (15, 16, 105).

For pdfFiller’s FAQs

What is Human Transforming Growth Factor β2 (hTGF-β2)?

Human Transforming Growth Factor β2 (hTGF-β2) is a cytokine that regulates a variety of cellular processes, including growth, differentiation, and immune responses. It plays a key role in tissue repair and fibrosis.

Who is required to file Human Transforming Growth Factor β2 (hTGF-β2)?

Entities such as clinical researchers, pharmaceutical companies, and laboratories involved in studies or applications that utilize hTGF-β2 for therapeutic or research purposes are generally required to file hTGF-β2 documentation.

How to fill out Human Transforming Growth Factor β2 (hTGF-β2)?

Filling out the hTGF-β2 documentation typically involves providing information on the study or application involving hTGF-β2, including but not limited to the research purpose, methodology, and anticipated outcomes.

What is the purpose of Human Transforming Growth Factor β2 (hTGF-β2)?

The purpose of hTGF-β2 is to facilitate communication between cells, particularly in processes related to immune function, wound healing, and the development of fibrotic tissue in various diseases.

What information must be reported on Human Transforming Growth Factor β2 (hTGF-β2)?

Reporting on hTGF-β2 typically includes details such as concentration, biological activity, source, method of production, and any relevant assay results that support the use of hTGF-β2 in the respective study or application.