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This document provides examples of ISBT 128 labels for various blood products, outlining the necessary information to record on the Transfusion Reaction Investigation Form (CM105).
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How to fill out transfusion reaction investigation form

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How to fill out Transfusion Reaction Investigation Form (CM105)

01
Begin by entering the patient's identification details at the top of the form.
02
Fill in the date and time the transfusion reaction occurred.
03
Indicate the type of transfusion that was administered (e.g., red blood cells, platelets).
04
Describe the signs and symptoms of the reaction observed in the patient.
05
Include vital signs and any changes noted during the reaction.
06
Document the immediate actions taken in response to the reaction.
07
List any medications administered as part of the treatment.
08
Provide details of the personnel notified about the reaction.
09
Complete the section regarding the patient's past transfusion history.
10
Sign and date the form before submitting it to the appropriate department.

Who needs Transfusion Reaction Investigation Form (CM105)?

01
The Transfusion Reaction Investigation Form (CM105) is needed by healthcare professionals involved in transfusion therapy, including nurses, doctors, and blood bank staff, to document and report any adverse reactions to blood transfusions.
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When a transfusion reaction is suspected, the transfusion should be immediately stopped, and the intravenous line should be kept open using appropriate fluids (usually 0.9% saline). A clerical check should be performed by examining the product bag and confirming the patient's identification.
In acute hemolytic reactions, the workup includes the following: Visual inspection of the recipient's plasma and . Retyping of donor and recipient red blood cells (RBCs) Direct antiglobulin (Coombs) testing.
Document the time and date of the reaction, type and amount of infused blood or blood product, time you started the transfusion, and time you stopped it.
Some symptoms may resolve with little or no treatment. However, respiratory distress, high fever, hypotension, and hemoglobinuria may indicate a more serious reaction. All cases of suspected reactions should prompt immediate discontinuation of the transfusion and notification of the blood bank and treating clinician.
Routine blood tests for Transfusion Reaction investigations; 6ml EDTA (pink) for repeat cross match and group and screen. 6ml clotted sample for U&E's, LFT's, LDH, Haptoglobin. 4ml EDTA (purple) for Full Blood Count. 2.7ml citrate (blue) for coagulation screen. sample (to check for haemoglobin / haematuria)
The three "R"s of blood transfusion in 2020; routine, reliable and robust.
Blood samples from the recipient (person getting the transfusion) and from the donor must be tested to tell whether symptoms are being caused by a transfusion reaction.

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The Transfusion Reaction Investigation Form (CM105) is a standardized document used to report and investigate adverse reactions that may occur following a blood transfusion. It helps ensure patient safety and facilitates the tracking of transfusion-related complications.
The Transfusion Reaction Investigation Form (CM105) must be filed by healthcare professionals, such as physicians, nurses, or transfusion service personnel, who are involved in the patient care during or after a blood transfusion when an adverse reaction is suspected.
To fill out the Transfusion Reaction Investigation Form (CM105), you must provide detailed information about the patient, transfusion details, the nature of the reaction, clinical observations, laboratory findings, and any interventions performed. It’s essential to complete all required fields accurately and in a timely manner.
The purpose of the Transfusion Reaction Investigation Form (CM105) is to systematically collect information about transfusion reactions to identify their causes, improve transfusion practices, enhance patient safety, and contribute to data collection for quality improvement initiatives in transfusion medicine.
The information that must be reported on the Transfusion Reaction Investigation Form (CM105) includes patient demographics, type of transfusion, volume of blood component transfused, time of transfusion, symptoms observed, onset time of the reaction, any relevant medical history, laboratory test results, and the actions taken in response to the reaction.
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