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This document outlines the protocol for the Magpie Trial, which aims to evaluate the effectiveness of magnesium sulphate as a treatment for women with pre-eclampsia, comparing it to a placebo in terms
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How to fill out magpie trial protocol
How to fill out Magpie Trial Protocol
01
Begin by downloading the Magpie Trial Protocol document from the official website.
02
Read the introductory section to understand the purpose of the protocol.
03
Fill out your personal information, including name, contact information, and role in the trial.
04
Enter the trial identification number and date in the designated sections.
05
Carefully follow the instructions for each section, ensuring all information is accurate and complete.
06
Provide details regarding the trial methodology, including participant enrollment criteria and data collection methods.
07
Outline the expected outcomes and any potential risks associated with the trial.
08
Review the filled-out document for errors or missing information.
09
Save the document in the required format and submit it as per the guidelines.
Who needs Magpie Trial Protocol?
01
Clinical researchers conducting trials involving Magpie treatment.
02
Ethics committees assessing the trial for approval.
03
Regulatory bodies requiring documentation for compliance.
04
Trial coordinators managing the logistics of the study.
05
Participants enrolled in the trial for their understanding of the protocol.
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People Also Ask about
What is the magpie technique?
Just as the magpie bird collects shiny objects from diverse places to build its sophisticated nest, the Magpie Method of innovation involves deliberately gathering ideas, techniques, and solutions from completely unrelated industries and adapting them to create something that appears revolutionary.
What was the result of the magpie trial?
Magnesium sulphate is the anticonvulsant of choice for women with eclampsia. The Magpie Trial showed that it is also effective for preventing the first eclamptic seizure, without substantive short-term harmful effects on either mother or baby.
What is the magpie regimen?
Magnesium sulphate is being compared to placebo. Both are given as a loading dose followed by 24 hours maintenance therapy. Each hospital decides whether to use the IM or IV regimen for maintenance therapy. The trial drug is supplied in numbered sealed treatment packs.
What is the number needed to treat magpie trial?
Women randomized to magnesium experienced a 58% lower risk of eclampsia (CI 40-71% reduced risk) compared to women allocated to placebo (RR 0.32, p<0.0001). The overall number needed to treat (NNT) to prevent one seizure was 91; among severe pre-eclamptics the NNT was 63 and among mild pre-eclamptics the NNT was 109.
What is the magpie strategy?
The magpie method encourages exploration, collaboration, and experimentation, ultimately leading to new insights and breakthroughs. Just as the magpie collects shiny objects to build its nest, individuals can collect diverse ideas, concepts, and perspectives to construct new and creative solutions.
What is the magpie regime?
Magnesium sulphate is being compared to placebo. Both are given as a loading dose followed by 24 hours maintenance therapy. Each hospital decides whether to use the IM or IV regimen for maintenance therapy. The trial drug is supplied in numbered sealed treatment packs.
What were the results of the Magpie trial?
This trial showed that magnesium sulphate halves the relative risk (RR) of eclampsia, without appearing to have substantive harmful effects on either the mother or the baby in the short term.
What was the conclusion of the Magpie trial?
Overall, 9024 children were included in the analysis of outcome at discharge from hospital. Magnesium sulphate more than halved the risk of eclampsia, and probably reduced the risk of maternal death. There did not appear to be any substantive harmful effects on the baby, in the short term.
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What is Magpie Trial Protocol?
The Magpie Trial Protocol is a structured guideline that outlines the procedures and requirements for conducting clinical trials to ensure they meet ethical and scientific standards.
Who is required to file Magpie Trial Protocol?
Researchers, sponsors, and institutions involved in the design and execution of clinical trials are required to file the Magpie Trial Protocol.
How to fill out Magpie Trial Protocol?
To fill out the Magpie Trial Protocol, researchers must provide comprehensive details regarding the trial design, objectives, methodology, participant criteria, data management, and ethical considerations, following the prescribed format.
What is the purpose of Magpie Trial Protocol?
The purpose of the Magpie Trial Protocol is to ensure the integrity, transparency, and reproducibility of clinical trials while safeguarding participant rights and safety.
What information must be reported on Magpie Trial Protocol?
The Magpie Trial Protocol must report information including trial title, objectives, methodology, participant demographics, safety assessments, and statistical analyses.
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