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Name: Date: Period: Pickleball Allele and Malaria The allele for sickle cell disease is most common in people of African ancestry. The reason for this probably has to do with the relationship between
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01
Understand the relationship between sickle-cell allele and malaria: Sickle-cell allele is a genetic mutation that can result in sickle cell disease, a condition that affects the shape and function of red blood cells. People with one copy of the sickle-cell allele have a lower risk of contracting malaria, while those with two copies of the allele (sickle cell trait) may have an increased risk of experiencing the complications of the disease.
02
Conduct genetic testing: To determine if someone has the sickle-cell allele, genetic testing can be done. This involves obtaining a sample, often through a blood test, and analyzing the DNA for the presence of the mutated gene. Consult a healthcare professional or genetic counselor to undergo the appropriate testing.
03
Understand the implications: Once the presence of the sickle-cell allele is confirmed, it is important to understand its implications. If someone has two copies of the sickle-cell allele, they have sickle cell disease. This condition can cause symptoms such as chronic pain, fatigue, and susceptibility to infections. It is essential to seek medical care and follow appropriate management strategies for this condition.
04
Monitor for malaria risk: If someone has one copy of the sickle-cell allele, they have sickle cell trait. While this can provide some protection against malaria, it is not foolproof, and individuals can still contract the disease. It is important to be aware of the risks associated with malaria and take precautions such as using insect repellents, sleeping under mosquito nets, and following any recommended preventive measures, particularly when traveling to regions where malaria is prevalent.

Who needs sickle-cell allele and malaria?

01
Individuals with sickle cell disease: People who have two copies of the sickle-cell allele need to be aware of their condition and seek appropriate medical care. It is important for them to work closely with healthcare professionals to manage the symptoms and complications of sickle cell disease, as well as take necessary precautions to prevent complications related to malaria.
02
Individuals with sickle cell trait: Individuals with one copy of the sickle-cell allele (sickle cell trait) may have a lower risk of contracting malaria. This can be particularly relevant for individuals living or traveling to areas where malaria is endemic. However, it is important to note that sickle cell trait does not provide complete immunity against malaria, and additional preventive measures should still be taken.
03
Healthcare professionals and genetic counselors: Medical professionals who work with individuals with sickle cell disease or sickle cell trait should have a thorough understanding of the relationship between sickle-cell allele and malaria. This knowledge allows them to provide appropriate care, advice, and genetic counseling to individuals and families affected by these conditions.
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Sickle-cell allele is a genetic variant that affects hemoglobin protein in the red blood cells, causing sickle-cell disease. Malaria is a disease caused by parasites that are transmitted through mosquito bites.
Medical professionals and researchers may be required to report cases of sickle-cell allele and malaria to health authorities.
Cases of sickle-cell allele and malaria can be reported through health records, laboratory tests, and other relevant medical documentation.
The purpose of reporting sickle-cell allele and malaria is to track the prevalence of these conditions, study their impact on public health, and implement strategies for prevention and treatment.
Information such as patient demographics, test results, and any relevant medical history should be included in reports of sickle-cell allele and malaria.
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