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Published March 1, 1987, IN VIVO APPLICATION OF RECOMBINANT INTERLEUKIN 2 IN THE IMMUNOTHERAPY OF ESTABLISHED CYTOMEGALOVIRUS INFECTION By MATTHIAS J. RELEASE, WOLFGANG MUTTER, ULRICH H. KALINOWSKI
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In vivo application refers to the use or testing of a substance or treatment in a living organism, typically an animal, for experimental or research purposes.
Researchers, scientists, or organizations conducting experiments or research involving the use of substances or treatments in living organisms are required to file in vivo application.
To fill out an in vivo application, the researcher or organization needs to provide detailed information about the experiment or research objectives, the substance or treatment being used, the species of the organism involved, the methodology, expected outcomes, safety measures, and ethical considerations. The application form can be obtained from the regulatory authority or relevant institution.
The purpose of in vivo application is to gain insights into the effects, efficacy, and safety of substances or treatments in a living organism before potential human trials. It helps researchers evaluate the potential benefits and risks associated with the intervention.
In an in vivo application, researchers must report information such as the study objectives, experimental design, potential risks or adverse effects, measures taken to ensure animal welfare and ethical considerations, as well as the expected outcomes or benefits of the study.
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