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INSTRUCTIONS TO PRINCIPAL INVESTIGATORS FOR COMPLETING
BIOLOGICAL USE AUTHORIZATION (BUA) APPLICATION FORMS
June 2000
1. What is a BUA? A BUA is a document describing a Principal Investigators (PI's)
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How to fill out instructions to principal investigators

Instructions to Principal Investigators:
01
Start by providing a clear and concise title or subject for the instructions. This will help the principal investigators quickly identify the purpose of the instructions and whether it is relevant to their work.
02
Begin with a brief introduction that explains the importance and context of the instructions. This can include information about any regulations or guidelines that the principal investigators need to adhere to, as well as any specific goals or objectives they should keep in mind.
03
Break down the instructions into specific sections or steps. Use bullet points or numbered lists to make it easier for the principal investigators to follow along. Ensure that each step is clearly described, providing any necessary details, examples, or references.
04
Include any necessary forms, templates, or documents that the principal investigators need to fill out or reference. Clearly label these attachments and provide detailed instructions on how to use them effectively.
05
If there are any deadlines or specific timelines associated with the instructions, clearly communicate them to the principal investigators. This will help them prioritize their tasks and ensure timely completion.
06
Provide contact information for any questions or clarifications regarding the instructions. Include the name of a point of contact, their email address, and phone number. Encourage the principal investigators to reach out for any necessary support or assistance.
Who needs instructions to principal investigators?
01
Research Compliance Officers: Research compliance officers play a crucial role in ensuring adherence to ethical and regulatory standards in research projects. They may need to provide instructions to principal investigators on specific protocols or procedures that need to be followed to maintain compliance.
02
Funding Agencies: Funding agencies that provide grants or support for research projects may require principal investigators to submit detailed instructions outlining how the funds will be allocated, how progress will be monitored, and any reporting requirements.
03
Institutional Review Boards (IRBs): IRBs oversee the ethical conduct of research involving human subjects. They may issue instructions to principal investigators on how to properly design and implement studies, obtain informed consent, and ensure participant confidentiality.
04
Research Institutions: Research institutions may have their own internal processes and guidelines that they need to communicate to principal investigators. These instructions could cover areas such as data management, intellectual property rights, safety protocols, and research publication policies.
05
Principal Investigators Themselves: Principal investigators may also need instructions for themselves, especially if they are new to the role or working on a project with unique requirements. These instructions can serve as a guide to help them navigate the various aspects of their research responsibilities effectively.
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What is instructions to principal investigators?
Instructions to principal investigators are guidelines provided to researchers conducting a study or project on how to manage and report their findings in compliance with regulations and policies.
Who is required to file instructions to principal investigators?
Principal investigators leading a study or project are required to file instructions to principal investigators.
How to fill out instructions to principal investigators?
Instructions to principal investigators can be filled out by detailing the necessary information and guidelines in the provided form.
What is the purpose of instructions to principal investigators?
The purpose of instructions to principal investigators is to ensure that research projects are conducted ethically, legally, and in compliance with regulations.
What information must be reported on instructions to principal investigators?
Information such as project details, ethical considerations, regulatory requirements, reporting guidelines, and budget details must be reported on instructions to principal investigators.
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