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PubMed 19951895 Nelson DR Goldstone JV Stegeman JJ. The cytochrome P450 genesis locus the origin and evolution of animal cytochrome P450s. J Appl Toxicol. 2012 32 707 713. PubMed 21425300 Honkakoski P Negishi M. Regulation of cytochrome P450 CYP genes by nuclear receptors. 4A a known ER agonist in zebrafish or T0901317 Fig. 4B a known LXR-FXR agonist in zebrafish. At the highest dose farnesol isomers FXR agonists in zebrafish and pregnenolone PXR content in embryos 48 h exposure Fig. T0901317...

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What is toxicology and applied pharmacology?

Toxicology and applied pharmacology is the branch of science that deals with the study of the adverse effects of chemicals on living organisms, as well as the study of how drugs interact with the body.

Who is required to file toxicology and applied pharmacology?

Researchers, pharmaceutical companies, and regulatory agencies are typically required to file toxicology and applied pharmacology reports.

How to fill out toxicology and applied pharmacology?

To fill out toxicology and applied pharmacology reports, one must gather and analyze data on the effects of chemicals or drugs on living organisms, and compile this information into a report that follows regulatory guidelines.

What is the purpose of toxicology and applied pharmacology?

The purpose of toxicology and applied pharmacology is to assess the safety and potential risks associated with the use of chemicals and drugs, and to inform regulatory decisions.

What information must be reported on toxicology and applied pharmacology?

Information such as study design, test results, conclusions, and potential risks must be reported on toxicology and applied pharmacology reports.

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