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Mediate Drugs (2013) 15:459471 DOI 10.1007/s4027201300344REVIEW ARTICLEManagement of Acute Rejection in Pediatric Liver Transplantation D. Thangarajah M. O'Meara A. DhawanPublished online: 8 August
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01
Step 1: Begin by conducting a thorough evaluation of the patient's medical history and current condition to confirm the presence of acute rejection.
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Step 2: Administer immunosuppressive medications as prescribed by the treating physician to prevent further rejection and suppress the immune response.
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Step 3: Monitor the patient closely for any signs or symptoms of acute rejection, such as fever, swelling, tenderness, or changes in organ function.
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Step 4: Perform regular biopsies or imaging studies to assess the progress of the management of acute rejection and make necessary adjustments to the treatment plan.
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Step 5: Collaborate with a multidisciplinary team of healthcare professionals, including transplant surgeons, nephrologists, and immunologists, to optimize the management of acute rejection.
06
Step 6: Educate the patient and their caregivers about the importance of medication adherence, lifestyle modifications, and regular follow-up appointments to ensure successful management of acute rejection.
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Step 7: Continuously monitor and adjust the immunosuppressive regimen based on the patient's response and risk of rejection, balancing the benefits and potential side effects of the medications.
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Step 8: Provide psychological support to the patient and address any concerns or anxieties they may have throughout the management of acute rejection process.
Who needs management of acute rejection?
01
Patients who have undergone solid organ transplantation, such as kidney, liver, heart, lung, or pancreas transplant, may require management of acute rejection.
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Individuals with a history of previous organ rejection or those who have high immunological risk factors may also need management of acute rejection.
03
Patients who have experienced signs or symptoms of acute rejection, as identified through diagnostic tests or clinical examination, should be considered for proper management.
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The decision for management of acute rejection is typically made by a transplant specialist or a multidisciplinary team of healthcare professionals based on each patient's individual circumstances and risk factors.
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