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NOTICE OF SUBSTANTIAL AMENDMENT For use in the case of all research other than clinical trials of investigational medicinal products (Chimps). For substantial amendments to Chimps, please use the

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What is notice of substantial amendment?

Notice of substantial amendment is a document that informs relevant parties about significant changes or modifications made to a previous agreement, contract, or plan.

Who is required to file notice of substantial amendment?

The party responsible for implementing the changes or modifications is typically required to file the notice of substantial amendment.

How to fill out notice of substantial amendment?

To fill out a notice of substantial amendment, one must provide details about the changes or modifications made, the reason for the changes, and any implications on the original agreement or plan.

What is the purpose of notice of substantial amendment?

The purpose of notice of substantial amendment is to ensure transparency and inform relevant parties about significant changes that may impact their rights, responsibilities, or interests.

What information must be reported on notice of substantial amendment?

The notice of substantial amendment must include information about the changes made, the reasons for the changes, the impact on the original agreement, and any required actions by the relevant parties.

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