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NOTICE OF SUBSTANTIAL AMENDMENT (longtime)For use in the case of all research other than clinical trials of investigational medicinal products (Chimps). For substantial amendments to Chimps, please
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What is NOTICE OF SUBSTANTIAL AMENDMENT (non-CTIMP) Form?

The NOTICE OF SUBSTANTIAL AMENDMENT (non-CTIMP) is a Word document which can be completed and signed for certain purpose. In that case, it is provided to the exact addressee in order to provide some information of any kinds. The completion and signing is available manually in hard copy or using a suitable tool like PDFfiller. Such services help to complete any PDF or Word file online. It also allows you to customize it depending on the needs you have and put a legal digital signature. Once finished, you send the NOTICE OF SUBSTANTIAL AMENDMENT (non-CTIMP) to the recipient or several recipients by email and also fax. PDFfiller includes a feature and options that make your blank printable. It provides a variety of options for printing out. It doesn't matter how you deliver a document - physically or by email - it will always look well-designed and firm. To not to create a new file from scratch again and again, make the original document into a template. After that, you will have a customizable sample.

NOTICE OF SUBSTANTIAL AMENDMENT (non-CTIMP) template instructions

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The notice of substantial amendment is a document informing about significant changes in an ongoing project or activity.
The entity or individual responsible for the project or activity is required to file the notice of substantial amendment.
The notice of substantial amendment can be filled out by providing details of the changes made to the project or activity, including reasons for the changes and expected impact.
The purpose of the notice of substantial amendment is to keep all stakeholders informed about significant changes that may affect the project or activity.
The notice of substantial amendment must include details of the changes made, reasons for the changes, expected impact, and any other relevant information.
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