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ISSN: 09758585 Research Journal of Pharmaceutical, Biological and Chemical Sciences In vivo anticancer activity of Clerodendrum erratum (L) moon. Ashish S. Zalke1×, Ashish V. Kulkarni1, Defend S.
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How to fill out in vivo anticancer activity:

01
Select the appropriate animal model: To begin, choose an animal model that closely mimics the type of cancer you are studying. Common animal models include mice, rats, and xenograft models.
02
Establish a suitable tumor model: Next, develop a tumor model in the selected animals. This may involve injecting cancer cells or using genetically engineered animals that spontaneously develop tumors.
03
Administer the anticancer treatment: Once the tumor model is established, administer the anticancer agent under investigation. This can be done through various routes such as oral gavage, intraperitoneal injection, intravenous injection, or subcutaneous injection.
04
Monitor tumor growth and treatment response: Regularly measure and record the size of the tumors to monitor their growth. Additionally, assess the treatment response by evaluating parameters like tumor volume, tumor weight, metastasis formation, and survival rates.
05
Conduct statistical analysis: After completing the experiments, perform statistical analysis to determine the significance of the results. This helps to establish the efficacy of the anticancer treatment in vivo.

Who needs in vivo anticancer activity?

In vivo anticancer activity is relevant to various stakeholders involved in cancer research and drug development. These include:
01
Pharmaceutical companies: Pharmaceutical companies require in vivo anticancer activity data to evaluate the effectiveness of potential drug candidates and make informed decisions regarding their development and clinical trials.
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Academic researchers: Academic researchers studying cancer biology, genetics, and therapeutic interventions often utilize in vivo models to understand the mechanisms of cancer development and test novel treatments.
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Regulatory authorities: Regulatory authorities, such as the Food and Drug Administration (FDA), require in vivo anticancer activity data as part of the preclinical evaluation process for new drugs. This data helps determine the safety and potential efficacy of the drug before it can be tested in humans.
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Clinicians and oncologists: In vivo anticancer activity data helps clinicians and oncologists stay updated with the latest advancements in cancer treatment. Understanding the effectiveness of various therapies allows them to make evidence-based decisions regarding patient care and treatment options.
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Patients: Ultimately, patients with cancer benefit from in vivo anticancer activity research as it contributes to the development of more effective and targeted therapies. This research helps improve survival rates, minimize side effects, and enhance the overall quality of life for cancer patients.
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In vivo anticancer activity refers to the testing of potential anticancer drugs on living organisms, typically animals.
Research institutions, pharmaceutical companies, and other organizations conducting anticancer drug research are required to file in vivo anticancer activity.
To fill out in vivo anticancer activity, researchers must document the test results, procedures, materials used, and any other relevant information in a standardized format.
The purpose of in vivo anticancer activity is to assess the effectiveness and safety of potential anticancer drugs in living organisms before human clinical trials.
Information such as the test results, procedures, materials used, dosage levels, and any adverse effects observed must be reported on in vivo anticancer activity.
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