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Protocol Title:A Randomized Clinical Trial of Aerobic Exercise Training in Older (50+ years) HIV infected AdultsSubTitle:Fitness and Longevity in Exercise (FLEX)Principal Investigator:Kris Ann Ouster,
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Step 1: Determine the research question or hypothesis that the randomized clinical trial aims to address.
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Step 2: Design the trial, including selecting the target sample size, randomization method, and inclusion/exclusion criteria.
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Step 3: Obtain ethical approval from the relevant research ethics committee.
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Step 4: Recruit eligible participants and obtain informed consent.
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Step 5: Randomly assign participants to either the experimental group or the control group.
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Step 6: Implement the intervention or treatment in the experimental group and the control group receives no intervention or a placebo.
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Step 7: Monitor and collect data on the outcomes of interest throughout the trial period.
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Step 10: Communicate and publish the trial results to contribute to the scientific knowledge.

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A randomized clinical trial is a type of scientific study in which participants are randomly assigned to different treatment groups in order to evaluate the effectiveness of a new treatment or intervention.
Researchers and organizations conducting clinical trials are required to file randomized clinical trials.
To fill out a randomized clinical trial, researchers need to follow protocol guidelines set by regulatory bodies and accurately record data on participant demographics, treatment protocols, and outcomes.
The purpose of a randomized clinical trial is to provide scientifically valid evidence on the safety and efficacy of new treatments or interventions.
Information that must be reported on a randomized clinical trial includes study design, participant eligibility criteria, treatment arms, outcomes measured, and statistical analysis plan.
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