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Project Number IND/IDE Number Date of this version: October 6, 2017, IND/IDE Holder To: Karim A., Pharma, Chair, IRB, NICHE Recommended by:Subject:,, ,,, 11CH0004 111,512 (Niacin) Jack YanovskiBranch

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Project number 11-ch-0004 is a confidential internal reference number.

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