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1MINISTRY OF HEALTH & FAMILY WELFARE National AIDS Control OrganizationNational AIDS Control Program (ACTIVE) NATIONAL COMPETITIVE BIDDINGeTENDER DOCUMENTForPROCUREMENT OF 3rd Line ARV Drugs (Raltegravir400
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01
Step 1: Choose an appropriate regimen for second-line treatment
02
Step 2: Include two nucleoside reverse transcriptase inhibitors (NRTIs) as the backbone of the regimen
03
Step 3: Select a boosted protease inhibitor (PI) or an integrase strand transfer inhibitor (INSTI) as the third drug
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Step 4: Administer the medication as prescribed by the healthcare provider
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Step 5: Attend regular follow-up visits and adhere to the treatment plan

Who needs second-line treatment of hiv-1?

01
Individuals with confirmed virologic failure on first-line treatment
02
Patients with drug resistance to the first-line regimen
03
People who experienced treatment interruptions or poor adherence to first-line therapy
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Any person with advanced HIV disease, including low CD4 count or high viral load
05
Pregnant women with high viral loads requiring antiretroviral therapy
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Second-line treatment of HIV-1 refers to the medications given to patients who have developed resistance to first-line antiretroviral drugs.
Healthcare providers and facilities are required to report second-line treatment of HIV-1 for their patients.
Second-line treatment of HIV-1 should be filled out with details of the specific antiretroviral drugs prescribed and any relevant patient information.
The purpose of second-line treatment of HIV-1 is to effectively manage the virus in patients who have developed resistance to first-line medications.
Information that must be reported includes the patient's name, date of birth, specific drugs prescribed, dosage, and any side effects experienced.
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