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This document is an undertaking form for professionals such as architects, engineers, and builders, to ensure compliance with the Karachi Building & Town Planning Regulations and to outline responsibilities
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What is the function of ZP2?
ZP2 zona pellucida glycoprotein 2 [ (human)] ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat. Novel variants in ZP1, ZP2 and ZP3 associated with empty follicle syndrome and abnormal zona pellucida. Novel Heterozygous Mutations in ZP2 Cause Abnormal Zona Pellucida and Female Infertility.
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ZP2 is the 'secondary receptor', which is cleaved by egg proteases after egg activation. The mouse ZP3 protein appears to be the 'primary receptor', which is responsible for species-specific binding of spermatozoa to the oocyte and the induction of the acrosome reaction.
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Form zp-2 is a specific tax or regulatory form used for reporting purposes in certain jurisdictions, often related to financial activities or compliance with regulations.
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