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HHS Public Access Author manuscript Author ManuscriptClin J Pain. Author manuscript; available in PMC 2016 December 01. Published in final edited form as: Clan J Pain. 2015 December ; 31(12): 10871096.
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To fill out a meta-analysis of risk factors, follow these steps:
02
Define the research question: Determine the specific risk factors you want to analyze and establish the objective of the meta-analysis.
03
Conduct a systematic literature review: Retrieve relevant studies from various sources, such as databases, journals, and grey literature.
04
Select studies for inclusion: Apply predefined inclusion and exclusion criteria to screen the retrieved studies. Only include studies that meet the specified criteria.
05
Extract data: Extract relevant data from the selected studies, including study characteristics, risk factor measurements, and outcomes.
06
Assess study quality: Evaluate the methodological quality and risk of bias of the included studies using appropriate assessment tools.
07
Perform statistical analysis: Use appropriate statistical methods to calculate effect sizes and combine the data from different studies.
08
Interpret the results: Interpret the findings of the meta-analysis, considering the overall effect size, heterogeneity, and potential sources of bias.
09
Conduct sensitivity analysis: Perform sensitivity analysis to assess the robustness of the results by excluding studies with certain characteristics or assessing the impact of outliers.
10
Report and publish the meta-analysis: Prepare a comprehensive report describing the methods, results, and conclusions of the meta-analysis. Submit the findings for publication in a relevant journal.

Who needs meta-analysis of risk factors?

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Meta-analysis of risk factors is useful for various individuals and groups, including:
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- Researchers: Conducting a meta-analysis helps researchers summarize and synthesize existing evidence on risk factors, providing a comprehensive overview of the topic.
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- Clinicians: Meta-analyses assist clinicians in making evidence-based decisions and recommendations for patient care, as they provide a higher level of evidence compared to individual studies.
04
- Policy makers: Meta-analyses inform policy makers about the associations between risk factors and outcomes, aiding in the development of public health policies and interventions.
05
- Journal editors and reviewers: Meta-analyses are valuable contributions to scientific literature, helping editors and reviewers evaluate the strength of evidence and potential bias in published studies.
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- Students and educators: Meta-analyses serve as educational resources, allowing students and educators to understand the collective findings of multiple studies and their implications.
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Meta-analysis of risk factors is a statistical method that combines results from multiple studies to identify and analyze the impact of various risk factors on a specific outcome or condition.
Researchers and organizations that conduct studies involving risk factors for health outcomes are typically required to file a meta-analysis of risk factors to provide a comprehensive overview of the findings.
Filling out a meta-analysis of risk factors involves collecting data from relevant studies, calculating effect sizes, assessing study quality, and synthesizing findings in a structured format that includes clear methodologies and results.
The purpose of meta-analysis of risk factors is to provide a more accurate and reliable estimate of the relationships between risk factors and outcomes by combining data from different studies, thus enhancing understanding and informing health policies.
Information that must be reported on meta-analysis of risk factors includes the studies included, data extraction methods, statistical analyses performed, results (including effect sizes), and any potential biases or limitations identified.
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