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Food and Drug Administration, HHS 1.235 (e) Update by CD-ROM for multiple submissions. If, for example, you do not have reasonable access to the Internet through any of the methods provided under
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How to fill out e update by CD-ROM:

01
Insert the CD-ROM into your computer's CD/DVD drive.
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Open the CD-ROM drive on your computer, and locate the e update file.
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Double-click on the e update file to initiate the installation process.
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Follow the on-screen prompts and instructions to complete the installation.
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Once the installation is finished, restart your computer if prompted to do so.

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Individuals who have purchased software or a program that requires regular updates.
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Anyone who wants to ensure that their software or program is running with the latest features, bug fixes, and security patches.
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