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READ ACROSS AMERICA March 2, 2020, MAINE EDUCATION ASSOCIATIONINCENTIVE GRANTSDeadline for Application: February 1, 2020, The MEA Strategic Budget provides $2,000 for incentive grants of up to $50
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To fill out read across, follow these steps:
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Start by identifying the substance or group of substances of interest, known as the source substance(s). This is the substance for which you have experimental data on toxicity, ecotoxicity, or other relevant endpoints.
03
Next, identify the target substance(s), which are the substances for which you want to predict or estimate the same properties as the source substance(s).
04
Gather all available data on the source substance(s) and the target substance(s). This may include information on physicochemical properties, toxicological endpoints, environmental fate, and other relevant data.
05
Compare the similarities and differences between the source substance(s) and the target substance(s). This can involve looking at structural similarities, functional groups, chemical reactivity, and other relevant factors.
06
Use scientific methods, such as QSAR models (Quantitative Structure-Activity Relationship), to make predictions or estimations for the target substance(s) based on the available data for the source substance(s).
07
Evaluate the reliability and validity of the predictions or estimations by considering the quality of the available data, the relevance of the source substance(s), and the applicability domain of the models used.
08
Document the read across process, including the rationale, data sources, methods used for prediction, and any uncertainties or limitations associated with the read across approach.
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Finally, communicate the results of the read across assessment, including the predicted or estimated properties of the target substance(s) and any associated uncertainties, to relevant stakeholders or regulatory bodies.

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Read across is useful for:
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- Regulatory authorities that need information on the potential hazards or risks of substances that have limited or no experimental data.
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- Chemical manufacturers or formulators who want to assess the safety and environmental impact of new substances or mixtures.
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- Researchers or scientists who need to make informed decisions about the potential hazards or risks of substances in their studies.
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- Risk assessors or toxicologists who need to evaluate the safety of substances for human health and the environment.
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- Companies or organizations involved in chemical risk assessment, management, or regulation.
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Read across refers to the transferability of information from one substance to another.
Companies or individuals who are involved in the production, import, or use of substances that are considered to be read across.
Read across can be filled out by providing relevant information about the substance being transferred, including data on its properties and behavior.
The purpose of read across is to avoid unnecessary animal testing and reduce the cost and time associated with regulatory compliance.
Information such as the chemical structure, physicochemical properties, toxicological data, and exposure information must be reported on read across.
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