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User Guide to the 2019 Fetal Death Public Use File2019 Fetal Death Data Set Users Guide ACKNOWLEDGMENTS Preparation of this users guide was coordinated by Elizabeth C.W. Gregory and Claudia P. Valenzuela
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How to fill out a patient-derived cell atlas

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How to fill out a patient-derived cell atlas

01
Collect patient samples, such as tissue or blood, to obtain the cells for the atlas.
02
Isolate the individual cells from the patient samples using techniques like fluorescence-activated cell sorting (FACS) or single-cell RNA sequencing.
03
Generate single-cell gene expression profiles by analyzing the RNA of each individual cell.
04
Cluster the cells based on their gene expression profiles to identify distinct cell types or states.
05
Apply computational tools and algorithms to annotate the identified cell types or states.
06
Validate the cell types or states by comparing them to known cell markers or biological features.
07
Create a data repository or database to store and share the patient-derived cell atlas.
08
Continuously update and refine the atlas as new data becomes available or as more patients are included.

Who needs a patient-derived cell atlas?

01
Researchers studying diseases and their underlying mechanisms can benefit from a patient-derived cell atlas.
02
The atlas can help identify specific cell types or states that are associated with certain diseases or conditions.
03
Pharmaceutical companies and drug discovery researchers can use the atlas to develop more targeted therapies and drugs.
04
Clinicians and healthcare providers can utilize the atlas to better understand disease progression and tailor treatments for individual patients.
05
The patient-derived cell atlas can also aid in personalized medicine and precision oncology by guiding diagnosis and treatment decisions.
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A patient-derived cell atlas is a collection of cellular data from individual patients, representing the diversity of cell types in the human body.
Researchers, scientists, and healthcare professionals who are studying human biology and diseases are typically the ones required to create and maintain patient-derived cell atlases.
To fill out a patient-derived cell atlas, researchers need to collect cellular data from individual patients, analyze and classify cell types, and organize the information in a structured format.
The purpose of a patient-derived cell atlas is to provide a comprehensive understanding of human cell diversity, which can help in studying diseases, developing therapies, and advancing personalized medicine.
Information such as cell types, cell markers, gene expressions, and spatial organization of cells must be reported on a patient-derived cell atlas.
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