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Get the free CRYSTALLINE FORMS OF (S)-7-(1,2,4TRIAZOLO1,5-aPYRIDIN-6-YL)-4-(3,4-DICHLOROHPHENYL)-...

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TEPZZ499B_T(19)(11)EP 2 429 293 B1EUROPEAN PATENT SPECIFICATION(12)(45) Date of publication and mention(51) Int Cl.:A01N 43/42 (2006.01) A61K 31/47 (2006.01)of the grant of the patent: 29.10.2014
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How to fill out crystalline forms of s-7-124triazolo15-apyridin-6-yl-4-34-dichlorohphenyl-1234-tetrahydroisoquinoline

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Begin by preparing a clean and sterile working area.
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Dissolve the weighed compound in a suitable solvent, such as ethanol or methanol, in a glass container.
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Slowly add a non-solvent, such as diethyl ether or hexane, to the solution while stirring. This will promote the formation of crystals.
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Allow the mixture to sit undisturbed for a period of time to allow the crystals to form. The time required may vary depending on the specific compound and desired crystalline form.
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Once the crystals have formed, carefully separate them from the liquid using filtration or decantation techniques.
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Wash the collected crystals with a small amount of a non-solvent to remove any impurities.
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Crystalline forms are different structures or arrangements of molecules in a solid state.
The entities involved in the development, production, or distribution of the compound may be required to file crystalline forms.
The forms should be filled out accurately with detailed information about the structure and characteristics of the crystalline forms.
The purpose is to provide a comprehensive understanding of the molecular structure of the compound in its solid form.
The information may include the crystal structure, polymorphic forms, and characterization data.
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