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Boris preprint DOI: https://doi.org/10.1101/2022.10.09.511456; this version posted October 11, 2022. The copyright holder for this preprint (which was not certified by peer review) is the author/funder.
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How to fill out network-based hub biomarker discovery

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Identify the specific biological network you want to explore
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Collect relevant omics data including gene expression, protein-protein interactions, and other molecular features
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Apply network analysis algorithms to identify hub nodes within the network
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Evaluate the identified hub biomarkers for their potential significance and role in the network
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Validate the hub biomarkers through experimental validation and functional studies

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Researchers studying complex diseases such as cancer, cardiovascular diseases, and neurological disorders
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Network-based hub biomarker discovery is a method that utilizes computational and mathematical approaches to identify key molecules (biomarkers) within biological networks that are associated with a particular disease or biological process.
Researchers, scientists, and healthcare professionals who are conducting studies related to biomarker discovery are required to file network-based hub biomarker discovery.
Network-based hub biomarker discovery can be filled out by providing information about the study design, data analysis methods, identified biomarkers, and their significance in the biological network.
The purpose of network-based hub biomarker discovery is to identify key molecules that can serve as potential biomarkers for early disease detection, prognosis, and treatment monitoring.
Information such as study objectives, methodology, data sources, identified biomarkers, statistical analysis, and biological implications must be reported on network-based hub biomarker discovery.
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