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Vol 4 Issue 3 2014 183189. International Journal of ISSN: 2248 9207 Print ISSN: 2248 9193 Pharmacy Review & Research www.ijprr.com FLOATING DRUG DELIVERY SYSTEM: A COMPREHENSIVE REVIEW AND ITS POSSIBLE

How to fill out floating drug delivery system

1. To fill out a floating drug delivery system, start by gathering all the necessary components. This typically includes the drug formulation, polymers, and any other materials needed for the system.
2. Next, accurately measure and weigh the drug formulation according to the predetermined dosage. This step ensures that the correct amount of medication will be delivered to the patient.
3. Combine the measured drug formulation with the appropriate polymers and other excipients. These polymers are responsible for forming the floating matrix, which helps the drug delivery system float in the stomach and release the medication slowly over time.
4. Mix the ingredients thoroughly to ensure uniform distribution. This step is crucial for consistent drug release and effectiveness of the system.
5. Once the mixture is well-blended, shape it into the desired form, such as tablets or capsules. The shape plays a role in the release kinetics and behavior of the floating drug delivery system.
6. Finally, package the filled floating drug delivery systems into suitable containers or blister packs. Proper packaging helps protect the system from moisture, light, and other external factors that could affect its performance.

Who needs a floating drug delivery system?

1. Patients with gastrointestinal disorders: Floating drug delivery systems are particularly useful for patients with gastrointestinal disorders like gastroparesis, acid reflux, or delayed gastric emptying. These conditions can affect the absorption and effectiveness of orally administered medications. The floating drug delivery system ensures prolonged drug release and targeted delivery to overcome these challenges.
2. Individuals requiring long-term medication: Patients who require medications for extended periods can benefit from floating drug delivery systems. These systems provide sustained release of drugs, reducing the frequency of dosing and improving patient compliance.
3. Doctors prescribing drugs with a narrow therapeutic index: Medications with a narrow therapeutic index require precise dosage and consistent blood levels to achieve optimal therapeutic outcomes without toxic effects. Floating drug delivery systems offer controlled drug release, avoiding high peaks and low troughs in drug concentration, thereby improving the safety and efficacy of such medications.

In summary, filling out a floating drug delivery system involves measuring and weighing the drug formulation, combining it with polymers, mixing thoroughly, shaping into desired forms, and packaging appropriately. Patients with gastrointestinal disorders, those requiring long-term medication, and individuals taking drugs with a narrow therapeutic index might benefit from using floating drug delivery systems.

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What is floating drug delivery system?

Floating drug delivery systems are drug delivery systems that are designed to float on the stomach contents and release the drug in a controlled manner.

Who is required to file floating drug delivery system?

Manufacturers and distributors of drug delivery systems are required to file floating drug delivery system.

How to fill out floating drug delivery system?

To fill out a floating drug delivery system, manufacturers and distributors must provide information on the design, release mechanism, and intended use of the drug delivery system.

What is the purpose of floating drug delivery system?

The purpose of a floating drug delivery system is to ensure targeted drug delivery to specific areas of the gastrointestinal tract, such as the stomach.

What information must be reported on floating drug delivery system?

Information that must be reported on floating drug delivery system includes design specifications, release mechanism details, intended use, and any relevant testing results.