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GastroPlusPBPK Modeling & Simulation Workshop April 29 30, University at Buffalo Who should attend? This workshop is appropriate for graduate students, research scientists, and engineers in the areas
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Define the physiological parameters of the model such as organ volumes, blood flow rates, and tissue composition.
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Specify the pharmacokinetic properties of the drug including absorption, distribution, metabolism, and excretion.
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Input the drug concentration-time profile data into the model.
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Run simulations to predict drug behavior in different scenarios or populations.
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Validate the model by comparing predicted outcomes with observed data.

Who needs pbpk modeling and simulationpbpk?

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Pharmaceutical companies developing new drugs
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Clinicians optimizing drug dosing for patients with complex pharmacokinetics
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Pbpk modeling and simulation helps to predict the concentration of a drug in different parts of the body over time.
Researchers, pharmaceutical companies, and regulatory agencies may be required to file pbpk modeling and simulation reports.
Pbpk modeling and simulation reports are typically filled out using specialized software and tools.
The purpose of pbpk modeling and simulation is to understand how a drug behaves within the body and how it is metabolized and excreted.
Information such as drug properties, physiological parameters, and model assumptions must be reported on pbpk modeling and simulation reports.
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